4-Oxofenretinide

CAS No. 865536-65-8

4-Oxofenretinide( 4-Oxo-4-HPR | 4-Oxo Fenretinide | 4-Keto-4-HPR )

Catalog No. M17628 CAS No. 865536-65-8

4-oxo-fenretinide, a recently identified fenretinide metabolite, induces marked G2-M cell cycle arrest and apoptosis.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 45 In Stock
5MG 65 In Stock
10MG 104 In Stock
25MG 185 In Stock
50MG 277 In Stock
100MG 500 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    4-Oxofenretinide
  • Note
    Research use only, not for human use.
  • Brief Description
    4-oxo-fenretinide, a recently identified fenretinide metabolite, induces marked G2-M cell cycle arrest and apoptosis.
  • Description
    4-Oxo-4-HPR is an inhibitor of tubulin polymerization, inducing marked G2-M cell cycle arrest and apoptosis in fenretinide-sensitive and fenretinide-resistant cell lines. It is also a fenretinide metabolite.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    4-Oxo-4-HPR | 4-Oxo Fenretinide | 4-Keto-4-HPR
  • Pathway
    GPCR/G Protein
  • Target
    Prostaglandin Receptor
  • Recptor
    cell cycle arrest and apoptosis
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    865536-65-8
  • Formula Weight
    405.53
  • Molecular Formula
    C26H31NO3
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    CC1=C(C(CCC1=O)(C)C)/C=C/C(=C/C=C/C(=C/C(=O)Nc1ccc(cc1)O)/C)/C
  • Chemical Name
    (2E,4E,6E,8E)-N-(4-Hydroxyphenyl)-3,7-dimethyl-9-(2,6,6-trimethyl-3-oxocyclohexen-1-yl)nona-2,4,6,8-tetraenamide

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Villani MG,et al. Cancer Res. 2006 Mar 15;66(6):3238-47.
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