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2′,2′-Difluorodeoxyuridine
CAS No. 114248-23-6
2′,2′-Difluorodeoxyuridine( —— )
Catalog No. M35912 CAS No. 114248-23-6
2′,2′-Difluorodeoxyuridine (dFdU), the major metabolite of Gemcitabine, exhibits anticancer and antitumor activities, shows radiosensitization under hypoxic conditions, and can be used to study pancreatic cancer.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 32 | In Stock |
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| 10MG | 46 | In Stock |
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| 25MG | 71 | In Stock |
|
| 50MG | 100 | In Stock |
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| 100MG | 147 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
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Biological Information
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Product Name2′,2′-Difluorodeoxyuridine
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NoteResearch use only, not for human use.
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Brief Description2′,2′-Difluorodeoxyuridine (dFdU), the major metabolite of Gemcitabine, exhibits anticancer and antitumor activities, shows radiosensitization under hypoxic conditions, and can be used to study pancreatic cancer.
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Description2′,2′-Difluorodeoxyuridine (dFdU) is the main metabolite of Gemcitabine (HY-17026). 2′,2′-Difluorodeoxyuridine causes a concentration- and schedule- dependent radiosensitising effect in vitro.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayOthers
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TargetOther Targets
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RecptorDrug Metabolite
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Research Area——
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Indication——
Chemical Information
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CAS Number114248-23-6
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Formula Weight264.18
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Molecular FormulaC9H10F2N2O5
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 125 mg/mL (473.16 mM; Ultrasonic ) H2O : 100 mg/mL (378.53 mM; Ultrasonic)
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SMILESOC[C@H]1O[C@@H](n2ccc(=O)[nH]c2=O)C(F)(F)[C@@H]1O
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Pauwels B, et al. The radiosensitising effect of difluorodeoxyuridine, a metabolite of gemcitabine, in vitro. Cancer Chemother Pharmacol. 2006 Aug;58(2):219-28.?
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