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23-Butanedione
CAS No. 431-03-8
23-Butanedione( Biacetyl | Diacetyl )
Catalog No. M19605 CAS No. 431-03-8
23-Butanedione (Diacetyl) the molecule implicated in the disease known as popcorn lung has now been implicated in amyloid-β peptide toxicity associated with Alzheimer’s disease. Diacetyl accelerates amyloid-β aggregation-a hallmark of Alzheimer’s disease.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
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Biological Information
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Product Name23-Butanedione
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NoteResearch use only, not for human use.
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Brief Description23-Butanedione (Diacetyl) the molecule implicated in the disease known as popcorn lung has now been implicated in amyloid-β peptide toxicity associated with Alzheimer’s disease. Diacetyl accelerates amyloid-β aggregation-a hallmark of Alzheimer’s disease.
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Description23-Butanedione (Diacetyl) the molecule implicated in the disease known as popcorn lung has now been implicated in amyloid-β peptide toxicity associated with Alzheimer’s disease. Diacetyl accelerates amyloid-β aggregation-a hallmark of Alzheimer’s disease. These preliminary findings raise the possibility of long-term neurological toxicity mediated by DA.
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In Vitro——
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In Vivo——
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SynonymsBiacetyl | Diacetyl
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PathwayOthers
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TargetOther Targets
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RecptorOthers
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Research Area——
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Indication——
Chemical Information
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CAS Number431-03-8
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Formula Weight86.09
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Molecular FormulaC4H6O2
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Purity>98% (HPLC)
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SolubilityDMSO:10 mM
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SMILESCC(=O)C(C)=O
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Heinitz K et al. Toxicity mediated by soluble oligomers of beta-amyloid(1-42) on cholinergic SN56.B5.G4 cells. J Neurochem. 2006 Sep;98(6):1930-45.
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