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20(R)-Propanaxadiol

CAS No. 38243-03-7

20(R)-Propanaxadiol( —— )

Catalog No. M18496 CAS No. 38243-03-7

20(R)-Propanaxadiol is a compound with anti-aging and antifatigue activities.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    20(R)-Propanaxadiol
  • Note
    Research use only, not for human use.
  • Brief Description
    20(R)-Propanaxadiol is a compound with anti-aging and antifatigue activities.
  • Description
    R-Ginsenodie Rg3 γ2 GABA-A receptor agonist, 7.1 K+ channel activator, α10 nAChR antagonist found in Panax. It exhibits a wide variety of biological activities, including decreasing expression of pro-inflammatory cytokines, reducing oxidative stress, and inhibiting tubular formation and migration of endothelial progenitor cells.
  • In Vitro
    ——
  • In Vivo
    Animal Model:Male Kunming mice weighing 18-22 g Dosage:0.05 mg/kg, 0.1 mg/kg, 0.5 mg/kg (5 μL each nostril) Administration:Intranasal administration; for 2 weeks Result:Significantly prolonged the weight-loaded swimming time, and also increased the hepatic glycogen levels.
  • Synonyms
    ——
  • Pathway
    Cell Cycle/DNA Damage
  • Target
    DNA/RNA Synthesis
  • Recptor
    Others
  • Research Area
    Others-Field
  • Indication
    ——

Chemical Information

  • CAS Number
    38243-03-7
  • Formula Weight
    785.02
  • Molecular Formula
    C42H72O13
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 41.67 mg/mL (53.08 mM)
  • SMILES
    C1[C@@H](C([C@H]2[C@](C1)([C@@H]1[C@@](CC2)([C@]2([C@H]([C@@H](C1)O)[C@H](CC2)[C@@](C)(CCC=C(C)C)O)C)C)C)(C)C)O[C@@H]1O[C@@H]([C@H]([C@@H]([C@H]1O[C@@H]1O[C@@H]([C@H]([C@@H]([C@H]1O)O)O)CO)O)O)CO
  • Chemical Name
    (2S,3R,4S,5S,6R)-2-(((2R,3R,4S,5S,6R)-4,5-dihydroxy-2-(((3R,5S,8R,9R,10R,12S,13R,14R,17S)-12-hydroxy-17-((S)-2-hydroxy-6-methylhept-5-en-2-yl)-4,4,10,13,14-pentamethylhexadecahydro-1H-cyclopenta[a]phenanthren-3-yl)oxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3-yl)oxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Bae EA,et al. Metabolism of 20(S)- and 20(R)-ginsenoside Rg3 by human intestinal bacteria and its relation to in vitro biological activities. Biol Pharm Bull. 2002 Jan;25(1):58-63.
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