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2-TEDC

CAS No. 132465-10-2

2-TEDC( —— )

Catalog No. M33822 CAS No. 132465-10-2

2-TEDC is a potent lipoxygenase (LOX) inhibitor with inhibitory effects on 5-LOX, 12-LOX, and 15-LOX with IC50 values of 0.09 μM, 0.013 μM, and 0.5 μM, respectively.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    2-TEDC
  • Note
    Research use only, not for human use.
  • Brief Description
    2-TEDC is a potent lipoxygenase (LOX) inhibitor with inhibitory effects on 5-LOX, 12-LOX, and 15-LOX with IC50 values of 0.09 μM, 0.013 μM, and 0.5 μM, respectively.
  • Description
    2-TEDC is a potent inhibitor of 5-, 12-, and 15-lipoxygenase with IC50 values of 0.09 μM, 0.013 μM and 0.5 μM, respectively. 2-TEDC can be used for the research of atheroscrelosi.
  • In Vitro
    2-TEDC can potent inhibit 5-, 12-, and 15-lipoxygenase with IC50 values of 0.09 μM, 0.013 μM and 0.5 μM, respectively.
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Immunology/Inflammation
  • Target
    Lipoxygenase
  • Recptor
    Lipoxygenase
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    132465-10-2
  • Formula Weight
    315.34
  • Molecular Formula
    C16H13NO4S
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 100 mg/mL (317.12 mM; Ultrasonic )
  • SMILES
    Oc1ccc(\C=C(/C#N)C(=O)OCCc2cccs2)cc1O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. H Cho, et al. Novel caffeic acid derivatives: extremely potent inhibitors of 12-lipoxygenase. J Med Chem. 1991 Apr;34(4):1503-5. ?
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