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Home - Products - Cell Cycle/DNA Damage - DNA/RNA Synthesis - 2-Fluoroadenine

2-Fluoroadenine

CAS No. 700-49-2

2-Fluoroadenine ( NSC 27364;2- Fluoro-6-Aminopurine )

Catalog No. M27216 CAS No. 700-49-2

2-Fluoroadenine has toxicity in nonproliferating and proliferating tumor cells. 2-Fluoroadenine can be used for anticancer studies.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    2-Fluoroadenine
  • Note
    Research use only, not for human use.
  • Brief Description
    2-Fluoroadenine has toxicity in nonproliferating and proliferating tumor cells. 2-Fluoroadenine can be used for anticancer studies.
  • Description
    2-Fluoroadenine has toxicity in nonproliferating and proliferating tumor cells. 2-Fluoroadenine can be used for anticancer studies.(In Vitro):In Balb-3T3 cells, 2-Fluoroadenine (0.22, 2.2 and 22 μM; 30 hours) inhibits protein, RNA, and DNA syntheses. In CEM cells, 2-Fluoroadenine (2 μM; 4 hours) inhibits CEM cell growth by targeting one or more enzymes involved in either RNA or protein synthesis. In nonproliferating MRC-5 cells, 2-Fluoroadenine (0-1000 μM; 96 hours) exhibits cytotoxicity.
  • Synonyms
    NSC 27364;2- Fluoro-6-Aminopurine
  • Pathway
    Cell Cycle/DNA Damage
  • Target
    DNA/RNA Synthesis
  • Recptor
    SARS-CoV
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    700-49-2
  • Formula Weight
    153.1
  • Molecular Formula
    C5H4FN5
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    Nc1[nH]c(F)nc2ncnc12
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Compound for treating diseases caused by coronavirus infection. Patent WO2018174442A1.
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