1NM-PP1 ( PP1 Analog II )

Catalog No. M13527 CAS No. 221244-14-0

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Datasheet

HNMR

HPLC

MSDS

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Product Name

1NM-PP1
Note

Research use only, not for human use.
Brief Description

1NM-PP1(PP1 Analog II) is a cell-permeable PP1 analog that acts as a potent and selective inhibitor of mutant kinases over their wild-type progenitors(IC50=28 uM vSrc; 4.2 nM v-Src-as1 I338G).
Description

1NM-PP1(PP1 Analog II) is a cell-permeable PP1 analog that acts as a potent and selective inhibitor of mutant kinases over their wild-type progenitors(IC50=28 uM vSrc; 4.2 nM v-Src-as1 I338G).
Synonyms

PP1 Analog II
Pathway

Angiogenesis
Target

CDK
Recptor

CDK7
Research Area

Cancer
Indication

——

CAS Number

221244-14-0
Formula Weight

331.41
Molecular Formula

C20H21N5
Purity

>98%(HPLC)
Solubility

DMSO: 10 mM
SMILES

NC1=C2C(N(C(C)(C)C)N=C2CC3=C4C=CC=CC4=CC=C3)=NC=N1
Chemical Name

1-(tert-butyl)-3-(naphthalen-1-ylmethyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine

1.Papa FR, et al. Science. 2003 Nov 28;302(5650):1533-7.

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