1NM-PP1

CAS No. 221244-14-0

1NM-PP1 ( PP1 Analog II )

Catalog No. M13527 CAS No. 221244-14-0

1NM-PP1(PP1 Analog II) is a cell-permeable PP1 analog that acts as a potent and selective inhibitor of mutant kinases over their wild-type progenitors(IC50=28 uM vSrc; 4.2 nM v-Src-as1 I338G).

Purity : >98%(HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 54 In Stock
5MG 73 In Stock
10MG 128 In Stock
25MG 272 In Stock
50MG 504 In Stock
100MG 669 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    1NM-PP1
  • Note
    Research use only, not for human use.
  • Brief Description
    1NM-PP1(PP1 Analog II) is a cell-permeable PP1 analog that acts as a potent and selective inhibitor of mutant kinases over their wild-type progenitors(IC50=28 uM vSrc; 4.2 nM v-Src-as1 I338G).
  • Description
    1NM-PP1(PP1 Analog II) is a cell-permeable PP1 analog that acts as a potent and selective inhibitor of mutant kinases over their wild-type progenitors(IC50=28 uM vSrc; 4.2 nM v-Src-as1 I338G).
  • Synonyms
    PP1 Analog II
  • Pathway
    Angiogenesis
  • Target
    CDK
  • Recptor
    CDK7
  • Research Area
    Cancer
  • Indication
    ——

Chemical Information

  • CAS Number
    221244-14-0
  • Formula Weight
    331.41
  • Molecular Formula
    C20H21N5
  • Purity
    >98%(HPLC)
  • Solubility
    DMSO: 10 mM
  • SMILES
    NC1=C2C(N(C(C)(C)C)N=C2CC3=C4C=CC=CC4=CC=C3)=NC=N1
  • Chemical Name
    1-(tert-butyl)-3-(naphthalen-1-ylmethyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Papa FR, et al. Science. 2003 Nov 28;302(5650):1533-7.
molnova catalog
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