inS3-54-A26, a novel inhibitor of the DNA-binding domain (DBD) of STAT3, suppresses tumor growth, metastasis and STAT3 target gene expression in vivo.

3-Hydroxymollugin are cytotoxic compounds isolated from Pentas longiflora and Rubia cordifolia.

Ergosterol peroxide is an inhibitor of osteoclast differentiation, which has antiviral, trypanocidal, antitumor, and antiangiogenic actions, it can stimulate Foxo3a activity by inhibiting pAKT and c-Myc and activating pro-apoptotic protein Puma and Bax to induce cancer cell death.