1-Methylxanthine

Research use only, not for human use.

1-Methylxanthine is a caffeine derivative. 1-Methylxanthine is an essential human urinary metabolite of caffeine and theophylline (1,3-dimethylxanthine, TP).

1-Methylxanthine is a caffeine derivative. 1-Methylxanthine is an essential human urinary metabolite of caffeine and theophylline (1,3-dimethylxanthine, TP). 1-Methylxanthine enhances the radiosensitivity of tumor cells.(In Vitro):1-Methylxanthine exhibits similar activities to other naturally occurring methylxanthines. Unlike caffeine and theobromine, 3-Methylxanthine, and 1-methylxanthine do not occur naturally at high levels in plants. 1-Methylxanthine (3 mM; for 30 min) increases the radiation-induced clonogenic and apoptotic cell (RKO human colorectal cancer cells carrying wild type protein 53 kDa (p53)) death.

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Proteasome/Ubiquitin

Endogenous Metabolite

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6136-37-4

166.1

C6H6N4O2

>98% (HPLC)

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Cn1c(=O)[nH]c2nc[nH]c2c1=O

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(-20℃)

With Ice Pack

≥ 2 years