1-Methylxanthine

CAS No. 6136-37-4

1-Methylxanthine( —— )

Catalog No. M26013 CAS No. 6136-37-4

1-Methylxanthine is a caffeine derivative. 1-Methylxanthine is an essential human urinary metabolite of caffeine and theophylline (1,3-dimethylxanthine, TP).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
50MG 37 In Stock
100MG Get Quote In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    1-Methylxanthine
  • Note
    Research use only, not for human use.
  • Brief Description
    1-Methylxanthine is a caffeine derivative. 1-Methylxanthine is an essential human urinary metabolite of caffeine and theophylline (1,3-dimethylxanthine, TP).
  • Description
    1-Methylxanthine is a caffeine derivative. 1-Methylxanthine is an essential human urinary metabolite of caffeine and theophylline (1,3-dimethylxanthine, TP). 1-Methylxanthine enhances the radiosensitivity of tumor cells.(In Vitro):1-Methylxanthine exhibits similar activities to other naturally occurring methylxanthines. Unlike caffeine and theobromine, 3-Methylxanthine, and 1-methylxanthine do not occur naturally at high levels in plants. 1-Methylxanthine (3 mM; for 30 min) increases the radiation-induced clonogenic and apoptotic cell (RKO human colorectal cancer cells carrying wild type protein 53 kDa (p53)) death.
  • In Vitro
    1-Methylxanthine (1-MTX; 3 mM; for 30 min) increases the radiation-induced clonogenic and apoptotic cell (RKO human colorectal cancer cells carrying wild type protein 53 kDa (p53)) death.1-Methylxanthine (1MX) exhibits similar activities to other naturally occurring methylxanthines. Unlike caffeine, TP, and theobromine, 3-Methylxanthine (3MX) and 1-methylxanthine do not occur naturally at high levels in plants.
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Proteasome/Ubiquitin
  • Target
    Endogenous Metabolite
  • Recptor
    ——
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    6136-37-4
  • Formula Weight
    166.14
  • Molecular Formula
    C6H6N4O2
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 10 mg/mL (60.19 mM)
  • SMILES
    Cn1c(=O)[nH]c2nc[nH]c2c1=O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Marks KR, et al. Synthesis and evaluation of 1-cyclopropyl-2-thioalkyl-8-methoxy fluoroquinolones.Bioorg Med Chem Lett. 2011 Aug 1;21(15):4585-8.
molnova catalog
related products
  • Oleamide

    Oleamide (Oleic acid amide) is an endogenous fatty acid amide and can be used in the synthesis of de novo in the mammalian nervous system.

  • Phosphonoacetic acid

    Phosphonoacetate also known as fosfonet or phosphonacetic acid belongs to the class of organic compounds known as organic phosphonic acids.Within the cell phosphonoacetate is primarily located in the cytoplasm. Phosphonoacetate can be biosynthesized from phosphonic acid and acetic acid.

  • Diethyl oxalpropiona...

    Diethyl oxalpropionate also known as methyloxalacetic acid diethyl ester or diethyl methyloxalacetate is a member of the class of compounds known as beta-keto acids and derivatives. These compounds are organic compounds containing an aldehyde substituted with a keto group on the C3 carbon atom.