Cart
sales@molnova.com
1-Hydroxyanthraquinone
CAS No. 129-43-1
1-Hydroxyanthraquinone ( —— )
Catalog No. M28115 CAS No. 129-43-1
1-Hydroxyanthraquinone is an anthraquinone that has been found in Morinda officinalis and has genotoxic and carcinogenic activities. 1-Hydroxyanthraquinone generates strong DNA repair response.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1G | 45 | In Stock |
|
Biological Information
-
Product Name1-Hydroxyanthraquinone
-
NoteResearch use only, not for human use.
-
Brief Description1-Hydroxyanthraquinone is an anthraquinone that has been found in Morinda officinalis and has genotoxic and carcinogenic activities. 1-Hydroxyanthraquinone generates strong DNA repair response.
-
Description1-Hydroxyanthraquinone is an anthraquinone that has been found in Morinda officinalis and has genotoxic and carcinogenic activities. 1-Hydroxyanthraquinone generates strong DNA repair response.(In Vitro):1-Hydroxyanthraquinone (5 and 500 μM) increases the percentage of isolated rat hepatocytes undergoing unscheduled DNA synthesis, indicating genotoxic activity.(In Vivo):Dietary administration of 1-Hydroxyanthraquinone (1%) induces formation of cecum and colon adenocarcinomas, as well as hepatocellular carcinomas, in rats.
-
Synonyms——
-
PathwayCell Cycle/DNA Damage
-
TargetDNA/RNA Synthesis
-
RecptorRORγt
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number129-43-1
-
Formula Weight224.2
-
Molecular FormulaC14H8O3
-
Purity>98% (HPLC)
-
Solubility——
-
SMILESOc1cccc2C(=O)c3ccccc3C(=O)c12
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1.BAKONYI J, et, al. Compounds as modulators of ror gamma. US20150291607A1.
molnova catalog
related products
-
ML-60218
ML-60218 (ML60218)is a broad-spectrum, small molecule inhibitor of RNA polymerase (Pol) III with IC50 of 32 and 27 uM for Saccharomyces cerevisiae and human, respectively.
-
SR15006
SR15006 is Krüppel-like factor 5 (KLF5) inhibitor (IC50 = 41.6 nM).
-
Juglone
Juglone is a natural naphthoquinone found in the black walnut (J. nigra) and other plants in the Juglandaceae family. Juglone also irreversibly inhibits peptidyl-prolyl cis/trans isomerases of the parvulin family including human Pin1 yeast Ess1/Ptf1 and E. coli parvulin (Ki = 55.9 nM).
