1,5-Isoquinolinediol

CAS No. 5154-02-9

1,5-Isoquinolinediol ( —— )

Catalog No. M17727 CAS No. 5154-02-9

1, 5-Isoquinolinediol is an inhibitor of poly(ADP-ribose) synthetase (PARP1; IC50: 0.39 μM).

Purity : 98%

COA Datasheet HNMR HPLC MSDS Handing Instructions
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10MG 78 In Stock
50MG 172 In Stock
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Biological Information

  • Product Name
    1,5-Isoquinolinediol
  • Note
    Research use only, not for human use.
  • Brief Description
    1, 5-Isoquinolinediol is an inhibitor of poly(ADP-ribose) synthetase (PARP1; IC50: 0.39 μM).
  • Description
    1, 5-Isoquinolinediol is an inhibitor of poly(ADP-ribose) synthetase (PARP1; IC50: 0.39 μM). The poly(ADP-ribose) polymerases (PARPs) form a family of enzymes with roles in DNA repair and apoptosis. 1, 5-Isoquinolinediol has been used to study the role of PARP1 in both DNA repair and oxidant stress-induced cell death. This compound can be used with cells in culture and in animals.
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    PARP1
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    5154-02-9
  • Formula Weight
    161.16
  • Molecular Formula
    C9H7NO2
  • Purity
    98%
  • Solubility
    ——
  • SMILES
    Oc1cccc2c1cc[nH]c2=O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Davar D, et al. Role of PARP inhibitors in cancer biology and therapy.[J]. Current Medicinal Chemistry, 2012, 19(23).
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