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Home - Products - Cell Cycle/DNA Damage - DNA/RNA Synthesis - 1,4-Dideoxy-1,4-epithio-D-ribitol

1,4-Dideoxy-1,4-epithio-D-ribitol

CAS No. 190315-43-6

1,4-Dideoxy-1,4-epithio-D-ribitol( —— )

Catalog No. M37903 CAS No. 190315-43-6

1,4-Dideoxy-1,4-epithio-D-ribitol is a purine nucleoside analog that targets malignant tumors of the inert lymphatic system and possesses a broad spectrum of antitumor activity.1,4-Dideoxy-1,4-epithio-D-ribitol induces apoptosis through inhibition of DNA synthesis.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    1,4-Dideoxy-1,4-epithio-D-ribitol
  • Note
    Research use only, not for human use.
  • Brief Description
    1,4-Dideoxy-1,4-epithio-D-ribitol is a purine nucleoside analog that targets malignant tumors of the inert lymphatic system and possesses a broad spectrum of antitumor activity.1,4-Dideoxy-1,4-epithio-D-ribitol induces apoptosis through inhibition of DNA synthesis.
  • Description
    (2R,3S,4R)-2-(Hydroxymethyl)tetrahydrothiophene-3,4-diol is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Cell Cycle/DNA Damage
  • Target
    DNA/RNA Synthesis
  • Recptor
    DNA/RNA Synthesis | Apoptosis | Nucleoside Antimetabolite/Analog
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    190315-43-6
  • Formula Weight
    150.2
  • Molecular Formula
    C5H10O3S
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    C(O)[C@@H]1[C@@H](O)[C@@H](O)CS1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.?
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