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(±)-BI-D

CAS No. 1416258-16-6

(±)-BI-D( —— )

Catalog No. M11732 CAS No. 1416258-16-6

A potent, allosteric HIV integrase inhibitor (Kd=34 nM) that binds the LEDGF/p75 binding site on integrase.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    (±)-BI-D
  • Note
    Research use only, not for human use.
  • Brief Description
    A potent, allosteric HIV integrase inhibitor (Kd=34 nM) that binds the LEDGF/p75 binding site on integrase.
  • Description
    A potent, allosteric HIV integrase inhibitor (Kd=34 nM) that binds the LEDGF/p75 binding site on integrase; inhibits the replication of NL4.3 virus (T124/T125) with EC50 of 51 nM.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Microbiology/Virology
  • Target
    HIV
  • Recptor
    HIV
  • Research Area
    Infection
  • Indication
    ——

Chemical Information

  • CAS Number
    1416258-16-6
  • Formula Weight
    405.4862
  • Molecular Formula
    C25H27NO4
  • Purity
    >98% (HPLC)
  • Solubility
    10 mM in DMSO
  • SMILES
    CC1=NC2=CC=CC=C2C(=C1C(C(=O)O)OC(C)(C)C)C3=CC4=C(C=C3)OCCC4
  • Chemical Name
    3-Quinolineacetic acid, 4-(3,4-dihydro-2H-1-benzopyran-6-yl)-α-(1,1-dimethylethoxy)-2-methyl-

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Fader LD, et al. ACS Med Chem Lett. 2014 Apr 16;5(6):711-6. 2. Wang H, et al. Nucleic Acids Res. 2012 Dec;40(22):11518-30.
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