(±)-BI-D
CAS No. 1416258-16-6
(±)-BI-D ( —— )
Catalog No. M11732 CAS No. 1416258-16-6
A potent, allosteric HIV integrase inhibitor (Kd=34 nM) that binds the LEDGF/p75 binding site on integrase.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
Size | Price / USD | Stock | Quantity |
50MG | 1341 | Get Quote |
|
100MG | 1791 | Get Quote |
|
200MG | Get Quote | Get Quote |
|
500MG | Get Quote | Get Quote |
|
1G | Get Quote | Get Quote |
|
Biological Information
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Product Name(±)-BI-D
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NoteResearch use only, not for human use.
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Brief DescriptionA potent, allosteric HIV integrase inhibitor (Kd=34 nM) that binds the LEDGF/p75 binding site on integrase.
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DescriptionA potent, allosteric HIV integrase inhibitor (Kd=34 nM) that binds the LEDGF/p75 binding site on integrase; inhibits the replication of NL4.3 virus (T124/T125) with EC50 of 51 nM.
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Synonyms——
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PathwayMicrobiology/Virology
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TargetHIV
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RecptorHIV
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Research AreaInfection
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Indication——
Chemical Information
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CAS Number1416258-16-6
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Formula Weight405.49
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Molecular FormulaC25H27NO4
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Purity>98% (HPLC)
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Solubility10 mM in DMSO
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SMILESCC1=NC2=CC=CC=C2C(=C1C(C(=O)O)OC(C)(C)C)C3=CC4=C(C=C3)OCCC4
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Chemical Name3-Quinolineacetic acid, 4-(3,4-dihydro-2H-1-benzopyran-6-yl)-α-(1,1-dimethylethoxy)-2-methyl-
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Fader LD, et al. ACS Med Chem Lett. 2014 Apr 16;5(6):711-6.
2. Wang H, et al. Nucleic Acids Res. 2012 Dec;40(22):11518-30.
2. Wang H, et al. Nucleic Acids Res. 2012 Dec;40(22):11518-30.
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