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(S)-Mephenytoin

CAS No. 70989-04-7

(S)-Mephenytoin( (+)-Mephenytoin )

Catalog No. M27425 CAS No. 70989-04-7

(S)-Mephenytoin ((+)-Mephenytoin) anticonvulsant effect. It is a substrate of the cytochrome P450 (CYP) isoform CYP2C19 and can be used to analyze cytochrome P450 metabolism.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    (S)-Mephenytoin
  • Note
    Research use only, not for human use.
  • Brief Description
    (S)-Mephenytoin ((+)-Mephenytoin) anticonvulsant effect. It is a substrate of the cytochrome P450 (CYP) isoform CYP2C19 and can be used to analyze cytochrome P450 metabolism.
  • Description
    (S)-Mephenytoin ((+)-Mephenytoin) anticonvulsant effect. It is a substrate of the cytochrome P450 (CYP) isoform CYP2C19 and can be used to analyze cytochrome P450 metabolism.(In Vivo):In the presence of cytochrome b5, the Km?for S-mephenytoin is 1.25 mM with all five purified cytochrome P-450s preparations.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    (+)-Mephenytoin
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Platelet aggregation
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    70989-04-7
  • Formula Weight
    218.25
  • Molecular Formula
    C12H14N2O2
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 66.67 mg/mL (305.48 mM)
  • SMILES
    CC[C@@](C(N1C)=O)(c2ccccc2)NC1=O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Zhao YF, et al. New transformation pathway and cytotoxic derivatives from the acid hydrolysis of timosaponin B III. Nat Prod Res. 2018 Nov 20:1-7.
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