α-Glucosidase-IN-22( —— )

Catalog No. M36060 CAS No. 2870693-28-8

α-Glucosidase-IN-22 is a selective inhibitor of α-glucosidase (IC50=0.64 μM). α-Glucosidase-IN-22 has antidiabetic activity and has potential in type 2 diabetes (T2DM) studies.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

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25MG	325	Get Quote
50MG	474	Get Quote
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Biological Information

Product Name

α-Glucosidase-IN-22
Note

Research use only, not for human use.
Brief Description

α-Glucosidase-IN-22 is a selective inhibitor of α-glucosidase (IC50=0.64 μM). α-Glucosidase-IN-22 has antidiabetic activity and has potential in type 2 diabetes (T2DM) studies.
Description

α-Glucosidase-IN-22 (compound 7i), a benzimidazole, is a potent α-glucosidase inhibitor with an IC50 of 0.64 μM. α-Glucosidase-IN-22 is a potent anti-diabetic agent and has the?potential?for?type 2 diabetes mellitus?(T2DM) research.
In Vitro

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In Vivo

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Synonyms

——
Pathway

Others
Target

Other Targets
Recptor

Glucosidase
Research Area

——
Indication

——

Chemical Information

CAS Number

2870693-28-8
Formula Weight

285.32
Molecular Formula

C14H11N3O2S
Purity

>98% (HPLC)
Solubility

In Vitro:?DMSO : 125 mg/mL (438.10 mM; Ultrasonic )
SMILES

N(=CC1=C(O)C=C(O)C=C1)C=2C=C3C(=CC2)NC(=S)N3
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Sardar Ali, et al. Novel 5-(Arylideneamino)-1?H-Benzo[?d]imidazole-2-thiols as Potent Anti-Diabetic Agents: Synthesis, In Vitro α-Glucosidase Inhibition, and Molecular Docking Studies. ACS Omega. 2022 Nov 23;7(48):43468-43479.?

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