Cart
sales@molnova.com
Home - Products - Others - Other Targets - yGsy2p-IN-1

yGsy2p-IN-1

CAS No. 2415003-97-1

yGsy2p-IN-1( —— )

Catalog No. M22548 CAS No. 2415003-97-1

yGsy2p-IN-1 is a potent yeast glycogen synthase 2 (yGsy2p) and human glycogen synthase 1 (hGYS1) inhibitor. yGsy2p-IN-H23 a pyrazole inhibitor,and is used for glycogen storage diseases (GSDs)

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 129 Get Quote
5MG 222 Get Quote
10MG 357 Get Quote
25MG 597 Get Quote
50MG 851 Get Quote
100MG 1152 Get Quote
200MG Get Quote Get Quote
500MG Get Quote Get Quote
1G Get Quote Get Quote
Get Quotation Bulk Inquiry Add to Cart

Biological Information

  • Product Name
    yGsy2p-IN-1
  • Note
    Research use only, not for human use.
  • Brief Description
    yGsy2p-IN-1 is a potent yeast glycogen synthase 2 (yGsy2p) and human glycogen synthase 1 (hGYS1) inhibitor. yGsy2p-IN-H23 a pyrazole inhibitor,and is used for glycogen storage diseases (GSDs)
  • Description
    yGsy2p-IN-1 is a potent yeast glycogen synthase 2 (yGsy2p) and human glycogen synthase 1 (hGYS1) inhibitor. yGsy2p-IN-H23 a pyrazole inhibitor,and is used for glycogen storage diseases (GSDs).
  • In Vitro
    yGsy2p-IN-1 (compound 23; 0.1, 1, 10, 100, 1000 μM) has IC50s of 7.89 μM and 33.6 μM for yGsy2p-WT and yGsy2p-Y513L. yGsy2p-IN-1 (100 μM) exhibits almost complete inhibition of synthase activity in both HEK293-PTG and Rat-1 cell lysates.
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    yGsy2p|Hgys1
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    2415003-97-1
  • Formula Weight
    352.26
  • Molecular Formula
    C16H11F3N2O4
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:62.5 mg/mL?(177.43 mM;?Need ultrasonic)
  • SMILES
    Oc1ccc(cc1)-c1c(n[nH]c1C(F)(F)F)-c1ccc(O)c(O)c1O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Buyun Tang, et al. Discovery and Development of Small-Molecule Inhibitors of Glycogen Synthase. J Med Chem. 2020 Apr 9;63(7):3538-3551.
Calculator

Molecular Weight Calculator

Dilution Calculator

Molarity Calculator

molnova catalog
related products

  • ZLDI-8

    ZLDI-8 is an inhibitor of Notch activating/cleaving enzyme ADAM-17 and inhibits the cleavage of Notch protein.ZLDI-8;?it inhibited the cleavage of NOTCH protein, consequently decreased the expression of pro-survival/anti-apoptosis and EMT related proteins.?

  • Sinocrassoside C1

    Sinocrassoside C1 is the methanolic extract of the whole plant of Sinocrassula indica (Crassulaceae), six new flavonol glycosides.

  • 2-Allylphenol

    2-Allylphenol exhibits antifungal activity.

Sign In Join Free