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toralactone

CAS No. 41743-74-2

toralactone( —— )

Catalog No. M24380 CAS No. 41743-74-2

Toralactone is a natural product isolated from Cassia obtusifolia, mediates hepatoprotection via an Nrf2-dependent anti-oxidative mechanism

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    toralactone
  • Note
    Research use only, not for human use.
  • Brief Description
    Toralactone is a natural product isolated from Cassia obtusifolia, mediates hepatoprotection via an Nrf2-dependent anti-oxidative mechanism
  • Description
    Toralactone is a natural product isolated from Cassia obtusifolia, mediates hepatoprotection via an Nrf2-dependent anti-oxidative mechanism.
  • In Vitro
    Toralactone sensitize resistant MCF-7adr cell line to paclitaxel via inhibiting P-glycoprotein efflux activity.
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Nuclear Receptor/Transcription Factor
  • Target
    Keap1-Nrf2
  • Recptor
    Nrf2
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    41743-74-2
  • Formula Weight
    272.25
  • Molecular Formula
    C15H12O5
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 2.5 mg/mL (9.18 mM)
  • SMILES
    O=C1C2=C(O)C3=C(O)C=C(OC)C=C3C=C2C=C(C)O1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Salwa D. Alqahtani, et al. Abstract 1205: Rubrofusarin and toralactone sensitize resistant MCF-7adr cell line to paclitaxel via inhibiting P-glycoprotein efflux activity. AACR Annual Meeting 2017; April 1-5, 2017; Washington, DC.
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