sphondin

CAS No. 483-66-9

sphondin ( —— )

Catalog No. M20453 CAS No. 483-66-9

Sphondin has anticonvulsant anti-inflammatory and anti-proliferative activities it possessed an inhibitory effect on IL-1beta-induced increase in the level of COX-2 protein and PGE(2) release in A549 cells.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 259 In Stock
10MG 437 In Stock
25MG 700 In Stock
50MG 963 In Stock
100MG 1287 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    sphondin
  • Note
    Research use only not for human use.
  • Brief Description
    Sphondin has anticonvulsant anti-inflammatory and anti-proliferative activities it possessed an inhibitory effect on IL-1beta-induced increase in the level of COX-2 protein and PGE(2) release in A549 cells.
  • Description
    Sphondin has anticonvulsant anti-inflammatory and anti-proliferative activities it possessed an inhibitory effect on IL-1beta-induced increase in the level of COX-2 protein and PGE(2) release in A549 cells.
  • Synonyms
    ——
  • Pathway
    Chromatin/Epigenetic
  • Target
    COX
  • Recptor
    COX-2;PGE2
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    483-66-9
  • Formula Weight
    216.19
  • Molecular Formula
    C12H8O4?
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    COc1cc2ccc(=O)oc2c2ccoc12
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Yang L L Liang Y C Chang C W et al. Effects of sphondin isolated from Heracleum laciniatum on IL–1β-induced cyclooxygenase-2 expression in human pulmonary epithelial cells[J]. Life Sciences 2002 72(2):199-213.
molnova catalog
related products
  • Aminophenazone

    Amidopyrine is a white crystalline substance used as an analgesic and antipyretic.A pyrazolone with analgesic anti-inflammatory and antipyretic properties but has risk of agranulocytosis.

  • Seratrodast

    Seratrodast (INN) is a thromboxane A2 (TXA2) receptor (TP receptor) antagonist used primarily in the treatment of asthma.

  • Vedaprofen

    Vedaprofen inhibits COX-1 and reduces prostaglandin H2 synthesis with anti-inflammatory activities. Vedaprofen is an inhibitor of Escherichia coli sliding clamp with the IC50 of 222 μM and Ki of 131 μM.