meplazumab
CAS No.
meplazumab ( —— )
Catalog No. M22102 CAS No.
meplazumab is a humanized anti-CD147 antibody, as add-on therapy in patients with COVID-19 pneumonia.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
Size | Price / USD | Stock | Quantity |
100MG | Get Quote | In Stock |
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200MG | Get Quote | In Stock |
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500MG | Get Quote | In Stock |
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1G | Get Quote | In Stock |
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Biological Information
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Product Namemeplazumab
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NoteResearch use only, not for human use.
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Brief Descriptionmeplazumab is a humanized anti-CD147 antibody, as add-on therapy in patients with COVID-19 pneumonia.
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Descriptionmeplazumab is a humanized anti-CD147 antibody, as add-on therapy in patients with COVID-19 pneumonia.Compared to control group, meplazumab treatment significantly improved the discharged (p=0.006) and case severity (p=0.021) in critical and severe patients.The time to virus negative in meplazumab group was reduced than that in control group (median 3, 95%CI[1.5-4.5] vs. 13, [6.5-19.5];p=0.014, HR=0.37, 95%CI[0.155-0.833]).The percentages of patients recovered to the normal lymphocyte count and CRP concentration were also increased remarkably and rapidly in meplazumab group.No adverse effect was found in meplazumab-treated patients.Interpretation:Meplazumab efficiently improved the recovery of patients with SARS-CoV-2 pneumonia with a favorable safety profile.
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Synonyms——
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PathwayOthers
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TargetOther Targets
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RecptorOthers
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Research Area——
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Indication——
Chemical Information
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CAS Number--
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Formula Weight——
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Molecular Formula——
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Purity>98% (HPLC)
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Solubility——
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SMILES——
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Huijie Bian, Zhao-Hui Zheng, Ding Wei,et al.Meplazumab treats COVID-19 pneumonia: an open-labelled, concurrent controlled add-on clinical trial.bioRxiv.2020.
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