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m-PEG3-SH

CAS No. 31521-83-2

m-PEG3-SH ( M-PEG3-Thiol; 2-(2-(2-Methoxyethoxy)Ethoxy)Ethanethiol )

Catalog No. M26973 CAS No. 31521-83-2

m-PEG3-SH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    m-PEG3-SH
  • Note
    Research use only, not for human use.
  • Brief Description
    m-PEG3-SH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
  • Description
    m-PEG3-SH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.(In Vitro):PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
  • Synonyms
    M-PEG3-Thiol; 2-(2-(2-Methoxyethoxy)Ethoxy)Ethanethiol
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Apoptosis; Bcr-Abl; HDAC
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    31521-83-2
  • Formula Weight
    180.3
  • Molecular Formula
    C7H16O3S
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    COCCOCCOCCS
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Rabizadeh E, et al. Pivanex, a histone deacetylase inhibitor, induces changes in BCR-ABL expression and when combined with STI571, acts synergistically in a chronic myelocytic leukemia cell line. Leuk Res. 2007 Aug;31(8):1115-23. Epub 2007 Jan 30.
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