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kauran-1617-diol

CAS No. 16836-31-0

kauran-1617-diol( —— )

Catalog No. M19790 CAS No. 16836-31-0

Kauran-16,17-diol (ent-Kauran-16β,17-diol), a natural diterpene, posseses anti-tumor and inducing-apoptosis activity, with a?IC50?of 17 μM on inhibiting NO production in LPS-stimulated RAW 264.7 macrophages.

Purity : >98% (HPLC)

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Biological Information

Product Name

kauran-1617-diol
Note

Research use only, not for human use.
Brief Description

Kauran-16,17-diol (ent-Kauran-16β,17-diol), a natural diterpene, posseses anti-tumor and inducing-apoptosis activity, with a?IC50?of 17 μM on inhibiting NO production in LPS-stimulated RAW 264.7 macrophages.
Description

Kauran-16,17-diol (ent-Kauran-16β,17-diol), a natural diterpene, posseses anti-tumor and inducing-apoptosis activity, with a?IC50?of 17 μM on inhibiting NO production in LPS-stimulated RAW 264.7 macrophages.
In Vitro

Kauran-16,17-diol (ent-Kauran-16β,17-diol) down-regulates Bcl-2 by disruption of the Ap-2α/Rb transcription activating complex and induces E2F1 up-regulation in MCF-7 cells.
In Vivo

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Synonyms

——
Pathway

Others
Target

Other Targets
Recptor

Others
Research Area

——
Indication

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Chemical Information

CAS Number

16836-31-0
Formula Weight

306.48
Molecular Formula

C20H34O2
Purity

>98% (HPLC)
Solubility

DMSO:10 mM
SMILES

CC1(C)CCC[C@@]2(C)[C@@H]3CC[C@@H]4C[C@]3(C[C@]4(O)CO)CC[C@H]12
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

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