hydrocotarnine ( —— )

Catalog No. M28624 CAS No. 550-10-7

hydrocotarnine?is an inhibitor of Cbl.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

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Biological Information

Product Name

hydrocotarnine
Note

Research use only, not for human use.
Brief Description

hydrocotarnine?is an inhibitor of Cbl.
Description

hydrocotarnine?is an inhibitor of Cbl.(In Vivo):In vivo, inhibition of Cbl with an analgesic drug, hydrocotarnine, increases inflammasome-mediated IL-18 secretion in the colon, and protects mice from dextran sulphate sodium-induced colitis. Together, our novel findings provide new insights into the role of the SFK-Cbl axis in suppressing NLRP3 inflammasome activation and identify a novel clinical utility of hydrocortanine for disease treatment.
Synonyms

——
Pathway

Others
Target

Other Targets
Recptor

——
Research Area

——
Indication

——

Chemical Information

CAS Number

550-10-7
Formula Weight

221.3
Molecular Formula

C12H15NO3
Purity

>98% (HPLC)
Solubility

——
SMILES

CN(CC1)Cc2c1cc1OCOc1c2OC
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1.Pedro Molina, et al. Iminophosphorane-mediated imidazole ring formation: A new and general entry to aplysinopsin-type alkaloids of marine origin. Tetrahedron Lett. 1994;50(7): 2241-2254

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