Cart
sales@molnova.com
hydrocotarnine
CAS No. 550-10-7
hydrocotarnine ( —— )
Catalog No. M28624 CAS No. 550-10-7
hydrocotarnine?is an inhibitor of Cbl.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 152 | Get Quote |
|
| 10MG | 237 | Get Quote |
|
| 25MG | 475 | Get Quote |
|
| 50MG | 692 | Get Quote |
|
| 100MG | 972 | Get Quote |
|
| 200MG | Get Quote | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
-
Product Namehydrocotarnine
-
NoteResearch use only, not for human use.
-
Brief Descriptionhydrocotarnine?is an inhibitor of Cbl.
-
Descriptionhydrocotarnine?is an inhibitor of Cbl.(In Vivo):In vivo, inhibition of Cbl with an analgesic drug, hydrocotarnine, increases inflammasome-mediated IL-18 secretion in the colon, and protects mice from dextran sulphate sodium-induced colitis. Together, our novel findings provide new insights into the role of the SFK-Cbl axis in suppressing NLRP3 inflammasome activation and identify a novel clinical utility of hydrocortanine for disease treatment.
-
Synonyms——
-
PathwayOthers
-
TargetOther Targets
-
Recptor——
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number550-10-7
-
Formula Weight221.3
-
Molecular FormulaC12H15NO3
-
Purity>98% (HPLC)
-
Solubility——
-
SMILESCN(CC1)Cc2c1cc1OCOc1c2OC
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1.Pedro Molina, et al. Iminophosphorane-mediated imidazole ring formation: A new and general entry to aplysinopsin-type alkaloids of marine origin. Tetrahedron Lett. 1994;50(7): 2241-2254
molnova catalog
related products
-
RK-33
RK-33 is a first-in-class small molecule inhibitor of DDX3 (a RNA helicase) and causes G1 cell cycle arrest, induces apoptosis, and promotes radiation sensitization in DDX3-overexpressing cells.
-
Trofinetide
Trofinetide (NNZ 2566 ) is a peptidomimetic tripeptide Gly-Pro-Glu that has anti-inflammatory and neuroprotective properties against hypoxic-ischemic brain injury and neurodegeneration.
-
Coixol
Coixol acts as a central muscle relaxant with an anti-convulsant effect.
