hCAII-IN-9

CAS No. 2878477-18-8

hCAII-IN-9( —— )

Catalog No. M36504 CAS No. 2878477-18-8

hCAII-IN-9 is a potent carbonic anhydrase inhibitor with IC50 values of 1.18 μM for hCA II, 0.17 μM for hCA IX, and 2.99 μM for hCA XII. It is not blood-brain barrier permeable.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 103 Get Quote
5MG 141 Get Quote
10MG 204 Get Quote
25MG 334 Get Quote
50MG 507 Get Quote
100MG 714 Get Quote
500MG 1467 Get Quote
1G Get Quote Get Quote

Biological Information

  • Product Name
    hCAII-IN-9
  • Note
    Research use only, not for human use.
  • Brief Description
    hCAII-IN-9 is a potent carbonic anhydrase inhibitor with IC50 values of 1.18 μM for hCA II, 0.17 μM for hCA IX, and 2.99 μM for hCA XII. It is not blood-brain barrier permeable.
  • Description
    hCAII-IN-9 is a potent carbonic anhydrase?inhibitor with IC50s of 1.18 μM (hCA II), 0.17 μM (hCA IX), and 2.99 μM (hCA XII), respectively. hCAII-IN-9 has no blood-brain barrier permeability.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Membrane Transporter/Ion Channel
  • Target
    Carbonic Anhydrase
  • Recptor
    Carbonic Anhydrase
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    2878477-18-8
  • Formula Weight
    417.89
  • Molecular Formula
    C15H16ClN3O5S2
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    S(N)(=O)(=O)C1=C(NC(=O)C2=CC(C)=CC(C)=C2)C=C(Cl)C(S(N)(=O)=O)=C1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Hussain Z, et al. Synthesis and Evaluation of Amide and Thiourea Derivatives as Carbonic Anhydrase (CA) Inhibitors. ACS Omega. 2022 Dec 6;7(50):47251-47264. ?
molnova catalog
related products
  • Histone acetyltransf...

    Histone acetyltransferase p300 Inhibitor 4c is a 2-aminothiazole derivative. Histone acetyltransferase p300 Inhibitor 4c inhibited hCA I, hCA II, AChE and BChE with Ki values of 0.008 ± 0.001, 0.124 ± 0.017, 0.129 ± 0.030 and 0.083 ± 0.041 μM. 0.017, 0.129 ± 0.030 and 0.083 ± 0.041 μM.

  • hCAI/II-IN-6

    hCAI/II-IN-6 is a selective and orally active inhibitor of human carbonic anhydrase (CA). hCAI/II-IN-6 inhibited hCA I, hCA II, hCA VII, and hCA XII with Ki values of 220, 4.9, 6.5, and >50,000 nM.

  • 4-Amino-6-(trifluoro...

    4-Amino-6-(trifluoromethyl)benzene-1,3-disulfonamide is a carbonic anhydrase inhibitor, used as a potential anti-tumor and antiglaucoma drug.