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d-Epigalbacin
CAS No. 84709-25-1
d-Epigalbacin( (-)-Zuonin A )
Catalog No. M29497 CAS No. 84709-25-1
d-Epigalbacin is a naturally occurring lignin. d-Epigalbacin is a potent, selective JNKs inhibitor, with IC50s of 1.7 μM, 2.9 μM and 1.74 μM for JNK1, JNK2 and JNK3, respectively.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 219 | Get Quote |
|
| 5MG | 357 | Get Quote |
|
| 10MG | 529 | Get Quote |
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| 25MG | 845 | Get Quote |
|
| 50MG | 1134 | Get Quote |
|
| 100MG | 1512 | Get Quote |
|
| 200MG | Get Quote | Get Quote |
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| 500MG | Get Quote | Get Quote |
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| 1G | Get Quote | Get Quote |
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Biological Information
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Product Named-Epigalbacin
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NoteResearch use only, not for human use.
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Brief Descriptiond-Epigalbacin is a naturally occurring lignin. d-Epigalbacin is a potent, selective JNKs inhibitor, with IC50s of 1.7 μM, 2.9 μM and 1.74 μM for JNK1, JNK2 and JNK3, respectively.
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Descriptiond-Epigalbacin is a naturally occurring lignin. d-Epigalbacin is a potent, selective JNKs inhibitor, with IC50s of 1.7 μM, 2.9 μM and 1.74 μM for JNK1, JNK2 and JNK3, respectively.(In Vitro):(?)-zuonin A binds the D-recruitment site of JNK. (?)-zuonin A inhibits the activation and phosphorylation of JNK by MKK4 and MKK7.
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In Vitro(?)-zuonin A binds the D-recruitment site (DRS) of JNK, a recruitment site utilized by substrates and other substrates to dock onto and recognize MAPKs.(?)-zuonin A inhibits the activation and phosphorylation of JNK by MKK4 and MKK7.
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In Vivo——
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Synonyms(-)-Zuonin A
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PathwayMAPK/ERK Signaling
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TargetJNK
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RecptorJNK
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Research Area——
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Indication——
Chemical Information
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CAS Number84709-25-1
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Formula Weight340.37
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Molecular FormulaC20H20O5
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 100 mg/mL (293.80 mM)
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SMILES——
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
molnova catalog
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d-Epigalbacin
d-Epigalbacin is a naturally occurring lignin. d-Epigalbacin is a potent, selective JNKs inhibitor, with IC50s of 1.7 μM, 2.9 μM and 1.74 μM for JNK1, JNK2 and JNK3, respectively.
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Norharmane
Norharmane is a natural β-carboline first isolated from plants of the Zygophyllaceae family.
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c-JUN peptide
Peptide comprising residues 33 - 57 of the JNK binding (δ) domain of human c-Jun. Disrupts JNK/c-Jun interaction leading to inhibition of serum-induced c-Jun phosphorylation, up-regulation of p21cip/waf and modulation of inflammatory gene expression. Specifically induces apoptosis in HeLa tumor cells.
