
cis-Anethol
CAS No. 104-46-1
cis-Anethol( Anethole | AI3-00380 | AI3 00380 | AI300380 | NSC 4018 )
Catalog No. M10221 CAS No. 104-46-1
Anethole is a type of aromatic compound that occurs widely in nature, widely used as a flavoring substance.
Purity : >98% (HPLC)






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Biological Information
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Product Namecis-Anethol
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NoteResearch use only, not for human use.
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Brief DescriptionAnethole is a type of aromatic compound that occurs widely in nature, widely used as a flavoring substance.
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DescriptionAnethole is a type of aromatic compound that occurs widely in nature, widely used as a flavoring substance.
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In Vitro——
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In VivoAnimal Model:BALB/C mice model induced by LPS Dosage:62.5 mg/kg, 125 mg/kg, 250 mg/kg, 500 mg/kg Administration:Intraperitoneal injection (i.p.), single dose. After LPS treatment (1.5 mg/kg; intratracheal injection, single dose).Result:Decreased total protein concentration. Decreased numbers of inflammatory cells including neutrophils and macrophages. Decreased the inflammatory mediators MMP-9, TNF-α, NO. Decreased LPS-induced histopathological changes. Suppressed the activation of NF-κB by blocking IκB-α degradation. Animal Model:Ehrlich ascites tumour (ETC) Swiss albino mouse modelDosage:250 mg/kg; 500 mg/kg; 1000 mg/kgn Administration:Oral gavage (p.o.); Once every other day for 60 consecutive days. After implantation of ETC cells (2.5×106 cells/mouse) into the right hind paw muscle of mice.Result:Reduced tumor weight and volume in mice.Prolonged the survival time of ETC mice.
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SynonymsAnethole | AI3-00380 | AI3 00380 | AI300380 | NSC 4018
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PathwayOthers
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TargetOther Targets
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RecptorOthers
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Research AreaOther Indications
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Indication——
Chemical Information
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CAS Number104-46-1
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Formula Weight148.2
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Molecular FormulaC10H12O
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Purity>98% (HPLC)
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SolubilityDMSO: 10 mM
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SMILESCOC1=CC=C(/C=C/C)C=C1
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Chemical NameAnisole, p-propenyl-
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Shimoni E, et al. J Biol Chem. 2002 Apr 5;277(14):11866-72.
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