cis-Anethol

CAS No. 104-46-1

cis-Anethol( Anethole | AI3-00380 | AI3 00380 | AI300380 | NSC 4018 )

Catalog No. M10221 CAS No. 104-46-1

Anethole is a type of aromatic compound that occurs widely in nature, widely used as a flavoring substance.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    cis-Anethol
  • Note
    Research use only, not for human use.
  • Brief Description
    Anethole is a type of aromatic compound that occurs widely in nature, widely used as a flavoring substance.
  • Description
    Anethole is a type of aromatic compound that occurs widely in nature, widely used as a flavoring substance.
  • In Vitro
    ——
  • In Vivo
    Animal Model:BALB/C mice model induced by LPS Dosage:62.5 mg/kg, 125 mg/kg, 250 mg/kg, 500 mg/kg Administration:Intraperitoneal injection (i.p.), single dose. After LPS treatment (1.5 mg/kg; intratracheal injection, single dose).Result:Decreased total protein concentration. Decreased numbers of inflammatory cells including neutrophils and macrophages. Decreased the inflammatory mediators MMP-9, TNF-α, NO. Decreased LPS-induced histopathological changes. Suppressed the activation of NF-κB by blocking IκB-α degradation. Animal Model:Ehrlich ascites tumour (ETC) Swiss albino mouse modelDosage:250 mg/kg; 500 mg/kg; 1000 mg/kgn Administration:Oral gavage (p.o.); Once every other day for 60 consecutive days. After implantation of ETC cells (2.5×106 cells/mouse) into the right hind paw muscle of mice.Result:Reduced tumor weight and volume in mice.Prolonged the survival time of ETC mice.
  • Synonyms
    Anethole | AI3-00380 | AI3 00380 | AI300380 | NSC 4018
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Others
  • Research Area
    Other Indications
  • Indication
    ——

Chemical Information

  • CAS Number
    104-46-1
  • Formula Weight
    148.2
  • Molecular Formula
    C10H12O
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO: 10 mM
  • SMILES
    COC1=CC=C(/C=C/C)C=C1
  • Chemical Name
    Anisole, p-propenyl-

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Shimoni E, et al. J Biol Chem. 2002 Apr 5;277(14):11866-72.
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