
c-Kit-IN-1
CAS No. 1225278-16-9
c-Kit-IN-1( —— )
Catalog No. M17203 CAS No. 1225278-16-9
DCC-2618 is an effective inhibitor of c-Met and c-Kit (IC50s<200 nM).
Purity : >98% (HPLC)






Size | Price / USD | Stock | Quantity |
2MG | 49 | In Stock |
![]() ![]() |
5MG | 80 | In Stock |
![]() ![]() |
10MG | 132 | In Stock |
![]() ![]() |
25MG | 288 | In Stock |
![]() ![]() |
50MG | 514 | In Stock |
![]() ![]() |
100MG | 737 | In Stock |
![]() ![]() |
500MG | 1521 | In Stock |
![]() ![]() |
1G | Get Quote | In Stock |
![]() ![]() |
Biological Information
-
Product Namec-Kit-IN-1
-
NoteResearch use only, not for human use.
-
Brief DescriptionDCC-2618 is an effective inhibitor of c-Met and c-Kit (IC50s<200 nM).
-
DescriptionDCC-2618 is an effective inhibitor of c-Met and c-Kit (IC50s<200 nM).(In Vitro):c-Kit-IN-1 is a c-Kit and c-Met inhibitor extracted from patent 2010051373A1, compound example 45, has an IC50 of <200 nM. c-Kit-IN-1 also inhibits KDR, PDGFR α and β with IC50s of <2 μM, <10 μM and <10 μM, respectively.
-
In Vitroc-Kit-IN-1 is a c-Kit and c-Met inhibitor extracted from patent 2010051373A1, compound example 45, has an IC50 of <200 nM. c-Kit-IN-1 also inhibits KDR, PDGFR α and β with IC50s of <2 μM, <10 μM and <10 μM, respectively.
-
In Vivo——
-
Synonyms——
-
PathwayEndocrinology/Hormones
-
TargetCaMK
-
Recptorc-Kit| c-Met
-
Research AreaCancer
-
Indication——
Chemical Information
-
CAS Number1225278-16-9
-
Formula Weight489.47
-
Molecular FormulaC26H21F2N5O3
-
Purity>98% (HPLC)
-
SolubilityDMSO : ≥ 100 mg/mL. 204.30 mM
-
SMILESCn1cc(cn1)c1nccc(c1)Oc1c(cc(c(c1)F)NC(=O)C1(CC1)C(=O)Nc1ccccc1)F
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Daniel L. Flynn, et al. Cyclopropane amides and analogs exhibiting anti-cancer and anti-proliferative activities. WO 2010051373 A1
molnova catalog



related products
-
KN-92 hydrochloride
KN-92 hydrochloride is an inactive derivative of KN-93. KN-93 is a selective Ca2+/calmodulin-dependent kinase II (CaMKII) inhibitor, competitively blocking CaM binding to the kinase with Ki of 370 nM.
-
Cloxacepride
cloxacepride is a CaM antagonist that is used to treat asthma disease.
-
Cinchonine
A local anesthetic of the amide type now generally used for surface anesthesia.