c-Kit-IN-1

CAS No. 1225278-16-9

c-Kit-IN-1( —— )

Catalog No. M17203 CAS No. 1225278-16-9

DCC-2618 is an effective inhibitor of c-Met and c-Kit (IC50s<200 nM).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 49 In Stock
5MG 80 In Stock
10MG 132 In Stock
25MG 288 In Stock
50MG 514 In Stock
100MG 737 In Stock
500MG 1521 In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    c-Kit-IN-1
  • Note
    Research use only, not for human use.
  • Brief Description
    DCC-2618 is an effective inhibitor of c-Met and c-Kit (IC50s<200 nM).
  • Description
    DCC-2618 is an effective inhibitor of c-Met and c-Kit (IC50s<200 nM).(In Vitro):c-Kit-IN-1 is a c-Kit and c-Met inhibitor extracted from patent 2010051373A1, compound example 45, has an IC50 of <200 nM. c-Kit-IN-1 also inhibits KDR, PDGFR α and β with IC50s of <2 μM, <10 μM and <10 μM, respectively.
  • In Vitro
    c-Kit-IN-1 is a c-Kit and c-Met inhibitor extracted from patent 2010051373A1, compound example 45, has an IC50 of <200 nM. c-Kit-IN-1 also inhibits KDR, PDGFR α and β with IC50s of <2 μM, <10 μM and <10 μM, respectively.
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Endocrinology/Hormones
  • Target
    CaMK
  • Recptor
    c-Kit| c-Met
  • Research Area
    Cancer
  • Indication
    ——

Chemical Information

  • CAS Number
    1225278-16-9
  • Formula Weight
    489.47
  • Molecular Formula
    C26H21F2N5O3
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO : ≥ 100 mg/mL. 204.30 mM
  • SMILES
    Cn1cc(cn1)c1nccc(c1)Oc1c(cc(c(c1)F)NC(=O)C1(CC1)C(=O)Nc1ccccc1)F
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Daniel L. Flynn, et al. Cyclopropane amides and analogs exhibiting anti-cancer and anti-proliferative activities. WO 2010051373 A1
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