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Ziprasidone
CAS No. 146939-27-7
Ziprasidone ( CP 88059;CP-88059;CP88059 )
Catalog No. M12007 CAS No. 146939-27-7
A full antagonist of D2 and 5-HT2A receptors with Ki of 6.8 and 0.6 nM, respectively; also is a partial agonist of 5-HT1A, and a partial antagonist of 5-HT2C and 5-HT1D receptors.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 10MG | 59 | In Stock |
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| 25MG | 92 | In Stock |
|
| 50MG | 148 | In Stock |
|
| 100MG | 192 | In Stock |
|
| 200MG | Get Quote | In Stock |
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| 500MG | Get Quote | In Stock |
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| 1G | Get Quote | In Stock |
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Biological Information
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Product NameZiprasidone
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NoteResearch use only, not for human use.
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Brief DescriptionA full antagonist of D2 and 5-HT2A receptors with Ki of 6.8 and 0.6 nM, respectively; also is a partial agonist of 5-HT1A, and a partial antagonist of 5-HT2C and 5-HT1D receptors.
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DescriptionA full antagonist of D2 and 5-HT2A receptors with Ki of 6.8 and 0.6 nM, respectively; also is a partial agonist of 5-HT1A, and a partial antagonist of 5-HT2C and 5-HT1D receptors; exhibits potent antipsychotic activity in vivo.Schizophrenia Approved
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SynonymsCP 88059;CP-88059;CP88059
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PathwayEndocrinology/Hormones
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Target5-HT Receptor
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Recptor5-HTtransporter;5-HT1A;5-HT1B;5-HT1D;5-HT2A;5-HT2C;5-HT6;5-HT7;D1;D2;D3;H1receptor;norepinephrinetransporter(NET);α1A-adrenergicreceptor;α2A-adrenergicreceptor
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Research AreaNeurological Disease
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IndicationSchizophrenia
Chemical Information
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CAS Number146939-27-7
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Formula Weight412.94
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Molecular FormulaC21H21ClN4OS
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Purity>98% (HPLC)
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Solubility10 mM in DMSO
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SMILESClC1=C(CCN2CCN(CC2)C2=NSC3=CC=CC=C23)C=C2CC(=O)NC2=C1
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Chemical Name2H-Indol-2-one, 5-[2-[4-(1,2-benzisothiazol-3-yl)-1-piperazinyl]ethyl]-6-chloro-1,3-dihydro-
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Mattei C, et al. J Cent Nerv Syst Dis. 2011 Feb 15;3:1-16.
2. Seeger TF, et al. J Pharmacol Exp Ther. 1995 Oct;275(1):101-13.
3. Schotte A, et al. Psychopharmacology (Berl). 1996 Mar;124(1-2):57-73.
2. Seeger TF, et al. J Pharmacol Exp Ther. 1995 Oct;275(1):101-13.
3. Schotte A, et al. Psychopharmacology (Berl). 1996 Mar;124(1-2):57-73.
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