Ziprasidone

CAS No. 146939-27-7

Ziprasidone ( CP 88059;CP-88059;CP88059 )

Catalog No. M12007 CAS No. 146939-27-7

A full antagonist of D2 and 5-HT2A receptors with Ki of 6.8 and 0.6 nM, respectively; also is a partial agonist of 5-HT1A, and a partial antagonist of 5-HT2C and 5-HT1D receptors.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
10MG 59 In Stock
25MG 92 In Stock
50MG 148 In Stock
100MG 192 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    Ziprasidone
  • Note
    Research use only, not for human use.
  • Brief Description
    A full antagonist of D2 and 5-HT2A receptors with Ki of 6.8 and 0.6 nM, respectively; also is a partial agonist of 5-HT1A, and a partial antagonist of 5-HT2C and 5-HT1D receptors.
  • Description
    A full antagonist of D2 and 5-HT2A receptors with Ki of 6.8 and 0.6 nM, respectively; also is a partial agonist of 5-HT1A, and a partial antagonist of 5-HT2C and 5-HT1D receptors; exhibits potent antipsychotic activity in vivo.Schizophrenia Approved
  • Synonyms
    CP 88059;CP-88059;CP88059
  • Pathway
    Endocrinology/Hormones
  • Target
    5-HT Receptor
  • Recptor
    5-HTtransporter;5-HT1A;5-HT1B;5-HT1D;5-HT2A;5-HT2C;5-HT6;5-HT7;D1;D2;D3;H1receptor;norepinephrinetransporter(NET);α1A-adrenergicreceptor;α2A-adrenergicreceptor
  • Research Area
    Neurological Disease
  • Indication
    Schizophrenia

Chemical Information

  • CAS Number
    146939-27-7
  • Formula Weight
    412.94
  • Molecular Formula
    C21H21ClN4OS
  • Purity
    >98% (HPLC)
  • Solubility
    10 mM in DMSO
  • SMILES
    ClC1=C(CCN2CCN(CC2)C2=NSC3=CC=CC=C23)C=C2CC(=O)NC2=C1
  • Chemical Name
    2H-Indol-2-one, 5-[2-[4-(1,2-benzisothiazol-3-yl)-1-piperazinyl]ethyl]-6-chloro-1,3-dihydro-

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Mattei C, et al. J Cent Nerv Syst Dis. 2011 Feb 15;3:1-16.
2. Seeger TF, et al. J Pharmacol Exp Ther. 1995 Oct;275(1):101-13.
3. Schotte A, et al. Psychopharmacology (Berl). 1996 Mar;124(1-2):57-73.
molnova catalog
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