Home - Products - Chromatin/Epigenetic - DNMT - Zebularine

Zebularine

CAS No. 3690-10-6

Zebularine( —— )

Catalog No. M14269 CAS No. 3690-10-6

Zebularine is a DNA methylation inhibitor that forms a covalent complex with DNA methyltransferases, also inhibits cytidinedeaminase with Ki of 2 μM in a cell-free assay.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

Size	Price / USD	Stock	Quantity
5MG	34	In Stock
10MG	52	In Stock
25MG	114	In Stock
50MG	206	In Stock
100MG	267	In Stock
200MG	Get Quote	In Stock
500MG	Get Quote	In Stock
1G	Get Quote	In Stock

Get Quotation Bulk Inquiry Add to Cart

Biological Information

Product Name

Zebularine
Note

Research use only, not for human use.
Brief Description

Zebularine is a DNA methylation inhibitor that forms a covalent complex with DNA methyltransferases, also inhibits cytidinedeaminase with Ki of 2 μM in a cell-free assay.
Description

Zebularine is a DNA methylation inhibitor that forms a covalent complex with DNA methyltransferases, also inhibits cytidinedeaminase with Ki of 2 μM in a cell-free assay.
In Vitro

——
In Vivo

——
Synonyms

——
Pathway

Chromatin/Epigenetic
Target

DNMT
Recptor

Cytidine deaminase
Research Area

Cardiovascular Disease
Indication

——

Chemical Information

CAS Number

3690-10-6
Formula Weight

228.2
Molecular Formula

C9H12N2O5
Purity

>98% (HPLC)
Solubility

Water: 46 mg/mL (201.57 mM); DMSO: 46 mg/mL (201.57 mM)
SMILES

C1=CN(C(=O)N=C1)[C@H]2[C@@H]([C@@H]([C@H](O2)CO)O)O
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1.Zhou L, et al. J Mol Biol, 2002, 321(4), 591-599.

Calculator

Molecular Weight Calculator

Dilution Calculator

Molarity Calculator

molnova catalog

related products

Dacogen

Decitabine is indicated for treatment of patients with myelodysplastic syndrome (MDS).
MC3343

MC3343 (MC-3343) is a novel potent, non-nucleoside DNA methyltransferase (DNMT) inhibitor with IC50 of 5.7 and 1.7 uM for DNMT1 and DNMT3a in cell-free assays, respectively.
SGI-110

A novel DNA hypomethylating dinucleotide that inhibits DNA methyltransferase (DNMT).

Sign In Join Free