ZINC13466751

CAS No. 117953-17-0

ZINC13466751( —— )

Catalog No. M26522 CAS No. 117953-17-0

ZINC13466751 is a potent HIF-1α/von Hippel-Lindau interaction inhibitor(IC50 = 2.0 μM).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 177 Get Quote
10MG 295 Get Quote
25MG 532 Get Quote
50MG 767 Get Quote
100MG 1053 Get Quote
500MG 2115 Get Quote
1G Get Quote Get Quote

Biological Information

  • Product Name
    ZINC13466751
  • Note
    Research use only, not for human use.
  • Brief Description
    ZINC13466751 is a potent HIF-1α/von Hippel-Lindau interaction inhibitor(IC50 = 2.0 μM).
  • Description
    ZINC13466751 is a potent HIF-1α/von Hippel-Lindau interaction inhibitor(IC50 = 2.0 μM).
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Angiogenesis
  • Target
    HIF/HIF Prolyl-hydroxylase
  • Recptor
    CYP2B6| CYP2C19
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    117953-17-0
  • Formula Weight
    363.421
  • Molecular Formula
    C20H21N5O2
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 50 mg/mL (137.59 mM)
  • SMILES
    CC1=NN(C(=O)\C1=N/Nc1ccc(cc1)N1CCOCC1)c1ccccc1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Vijayabhaskar V, Srivastava P, Rajagopal S. Breaking the sensitivity limitations of cytochrome P450 oxidation product: dansyl chloride derivatisation of 4-OH mephenytoin, a CYP2C19 metabolite and its application to in vitro CYP inhibition assay. J Chromatogr B Analyt Technol Biomed Life Sci. 2015 May 1;989:27-36.
molnova catalog
related products
  • ML228

    ML228 (ML-228, CID-46742353) is an activator of the hypoxia inducible factor (HIF) pathway with EC50 of 1.4 uM in HIF-1α nuclear translocation assays.

  • HIF-IN-1

    HIF-IN-1 is a potent inhibitor of hypoxia-inducible factor (HIF-1), which is associated with tumor and cancer cell proliferation and inhibits HIF-1α protein aggregation.

  • TP-0463518

    TP-0463518 is a novel, highly potent HIF prolyl hydroxylase (PHD) inhibitor.