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Home - Products - Membrane Transporter/Ion Channel - P-glycoprotein - YS-370

YS-370

CAS No. 2470908-79-1

YS-370( —— )

Catalog No. M28486 CAS No. 2470908-79-1

YS-370 is an orally active inhibitor of P-gp and shows moderate inhibition against CYP3A4. YS-370 effectively reverses multidrug resistance to paclitaxel and colchicine and exhibits stronger antitumor activity in combination with paclitaxel.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 132 Get Quote
5MG 222 Get Quote
10MG 357 Get Quote
25MG 597 Get Quote
50MG 851 Get Quote
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Biological Information

  • Product Name
    YS-370
  • Note
    Research use only, not for human use.
  • Brief Description
    YS-370 is an orally active inhibitor of P-gp and shows moderate inhibition against CYP3A4. YS-370 effectively reverses multidrug resistance to paclitaxel and colchicine and exhibits stronger antitumor activity in combination with paclitaxel.
  • Description
    YS-370 is an orally active inhibitor of P-gp and shows moderate inhibition against CYP3A4. YS-370 effectively reverses multidrug resistance to paclitaxel and colchicine and exhibits stronger antitumor activity in combination with paclitaxel.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Membrane Transporter/Ion Channel
  • Target
    P-glycoprotein
  • Recptor
    enpp-1
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    2470908-79-1
  • Formula Weight
    663.6
  • Molecular Formula
    C37H35BrN4O3
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 8.33 mg/mL (12.55 mM)
  • SMILES
    BrC=1C=CC=CC1CN2C=3C=CC=CC3C(C=4N=CN=C5C=C(OC)C(OCCCN6CCOCC6)=CC54)=C2C=7C=CC=CC7
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

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