Xyloidone

CAS No. 15297-92-4

Xyloidone ( Dehydro-α-lapachone; NSC-106453; NSC106453; NSC 629748; Dehydrolapachone; Dehydrolapachone; )

Catalog No. M27202 CAS No. 15297-92-4

Xyloidone exhibits antifungal activity and completely inhibits the mycelial growth of B. cinerea, Colletotrichum acutatum Simmonds, Colletotrichum gloeosporioides Simmonds, M. grisea, and Pythium ultimum Trow over a range of 0.4-33.3 mg/L.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 242 In Stock
10MG 356 In Stock
25MG 593 In Stock
100MG Get Quote In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
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Biological Information

  • Product Name
    Xyloidone
  • Note
    Research use only, not for human use.
  • Brief Description
    Xyloidone exhibits antifungal activity and completely inhibits the mycelial growth of B. cinerea, Colletotrichum acutatum Simmonds, Colletotrichum gloeosporioides Simmonds, M. grisea, and Pythium ultimum Trow over a range of 0.4-33.3 mg/L.
  • Description
    Xyloidone exhibits antifungal activity and completely inhibits the mycelial growth of B. cinerea, Colletotrichum acutatum Simmonds, Colletotrichum gloeosporioides Simmonds, M. grisea, and Pythium ultimum Trow over a range of 0.4-33.3 mg/L.(In Vitro):Xyloidone controlls the development of rice blast, tomato late blight, wheat leaf rust, barley powdery mildew and red pepper anthracnose (Colletotrichum coccodes (Wallr) S Hughes). Xyloidone is particularly effective in suppressing red pepper anthracnose by 95% at a concentration of 125 mg/L.(In Vivo):Xyloidone inhibits vessel regeneration, interferes with vessel anastomosis, and limits plexus formation in zebrafish. Xyloidone induces vascular pruning and growth delay in orthotopic mammary tumors in mice. Xyloidone targets cell adhesion by promoting ubiquitination of the Rho-GTPase Rac1, which is frequently up-regulated in many different cancers.
  • Synonyms
    Dehydro-α-lapachone; NSC-106453; NSC106453; NSC 629748; Dehydrolapachone; Dehydrolapachone;
  • Pathway
    GPCR/G Protein
  • Target
    Antibacterial
  • Recptor
    NK1
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    15297-92-4
  • Formula Weight
    240.3
  • Molecular Formula
    C15H12O3
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    CC1(C)OC2=C(C=C1)C(=O)c1ccccc1C2=O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Gackenheimer SL, et al. In vitro and ex vivo autoradiography of the NK-1 antagonist [3H]-LY686017 in Guinea pig brain. Neuropeptides. 2011 Apr;45(2):157-64.
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