XL-001 ( XL001 )

Catalog No. M11799 CAS No. 1426153-46-9

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HNMR

HPLC

MSDS

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Product Name

XL-001
Note

Research use only, not for human use.
Brief Description

XL-001 (XL001) is a novel specific CB2 inverse agonist with Ki of 0.5 nM.
Description

XL-001 (XL001) is a novel specific CB2 inverse agonist with Ki of 0.5 nM; inhibits in a dose-dependent fashion the fibrogenic response induced by CB2 overexpression, CB2 agonist or transforming growth factor-β1, ameliorates kidney injury, fibrosis and inflammation in both the obstruction and ischemia/reperfusion models.
Synonyms

XL001
Pathway

GPCR/G Protein
Target

Cannabinoid Receptor
Recptor

Cannabinoid Receptor
Research Area

——
Indication

——

CAS Number

1426153-46-9
Formula Weight

438.59
Molecular Formula

C25H30N2O3S
Purity

>98% (HPLC)
Solubility

——
SMILES

CCN(CC)C1=CC=C(C=C1)CN(C2=CC=C(C=C2)C)S(=O)(=O)C3=CC=C(C=C3)OC
Chemical Name

N-(4-(diethylamino)benzyl)-4-methoxy-N-(p-tolyl)benzenesulfonamide

1. Zhou L, et al. Kidney Int. 2018 Aug 6. pii: S0085-2538(18)30397-1.

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