XEN-402 ( Funapide;TV-45070 )

Catalog No. M11070 CAS No. 1259933-16-8

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HNMR

HPLC

MSDS

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Product Name

XEN-402
Note

Research use only, not for human use.
Brief Description

XEN-402 (Funapide;TV-45070) is a potent and selective, orally available sodium channel Nav1.7 and Nav1.8 blocker for treatment of pain.
Description

XEN-402 (Funapide;TV-45070) is a potent and selective, orally available sodium channel Nav1.7 and Nav1.8 blocker for treatment of pain. Pain Phase 2 Clinical
Synonyms

Funapide;TV-45070
Pathway

Membrane Transporter/Ion Channel
Target

Sodium Channel
Recptor

Sodium Channel
Research Area

Neurological Disease
Indication

Pain

CAS Number

1259933-16-8
Formula Weight

429.35
Molecular Formula

C22H14F3NO5
Purity

>98% (HPLC)
Solubility

——
SMILES

O=C([C@]12COC3=C1C=C(OCO4)C4=C3)N(CC5=CC=C(C(F)(F)F)O5)C6=C2C=CC=C6
Chemical Name

(3'S)-1'-{[5-(trifluoromethyl)furan-2-yl]methyl}-2H,6H-spiro[furo[2,3-f][1,3]benzodioxole-7,3'-indol]-2'(1'H)-one

1. Bagal SK, et al. Bioorg Med Chem Lett. 2014 Aug 15;24(16):3690-9.
2. Goldberg YP, et al. Pain. 2012 Jan;153(1):80-5.

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