Wnt-C59 ( PORCN Inhibitor II )

Catalog No. M10985 CAS No. 1243243-89-1

COA

Datasheet

HNMR

HPLC

MSDS

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Product Name

Wnt-C59
Note

Research use only, not for human use.
Brief Description

Wnt-C59(C59) is a very potent and highly selective Wnt signaling antagonist with an IC50 ~ 74 pM in the Wnt signaling reporter assay.
Description

Wnt-C59(C59) is a very potent and highly selective Wnt signaling antagonist with an IC50 ~ 74 pM in the Wnt signaling reporter assay.
Synonyms

PORCN Inhibitor II
Pathway

Wnt/Notch/Hedgehog
Target

Porcupine
Recptor

Porcn
Research Area

Cancer
Indication

——

CAS Number

1243243-89-1
Formula Weight

379.45
Molecular Formula

C25H21N3O
Purity

>98%(HPLC)
Solubility

DMSO: 76 mg/mL (200.28 mM)
SMILES

O=C(NC1=CC=C(C2=CC=CN=C2)C=C1)CC3=CC=C(C4=CC(C)=NC=C4)C=C3
Chemical Name

2-(4-(2-methylpyridin-4-yl)phenyl)-N-(4-(pyridin-3-yl)phenyl)acetamide

1.Proffitt KD, et al. Y Res. 2013 Jan 15;73(2):502-7.

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