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Wistin

CAS No. 19046-26-5

Wistin( —— )

Catalog No. M32604 CAS No. 19046-26-5

Wistin, isolated from Caragana sinica roots, is a PPARα and PPARγ agonist.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Wistin
  • Note
    Research use only, not for human use.
  • Brief Description
    Wistin, isolated from Caragana sinica roots, is a PPARα and PPARγ agonist.
  • Description
    Wistin, isolated from Caragana sinica roots, is a PPARα and PPARγ agonist.
  • In Vitro
    Wistin, is a PPARγ agonist that can induce the mRNA expression of the PPARγ target gene adiponectin in mouse 3T3-L1 cells.Wistin inhibits cellular triglyceride accumulation in hepatocytes (P<0.05 at 10 μg/mL) in a dose-dependent manner.Wistin (10 μg/mL) results in a 2.5-, 7.2-, and 14.8-fold increase in the expression levels of CPT1a, ACO, and ACS, respectively.Treatment with Wistin for 48 h significantly decreases the amount of cellular TG in mouse primary hepatocytes in a dose-dependent manner.Treatment with wistin enhanced the marker of adipocyte differentiation, such as triglyceride accumulation in 3T3-L1 cells. RT-PCR Cell Line:Mouse hepatocytes.Concentration:1 or 10 μg/mL.Incubation Time:48 h.Result:Significantly increased PPARα mRNA levels in a dose-dependent manner.
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    ——
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    19046-26-5
  • Formula Weight
    460.4
  • Molecular Formula
    C23H24O10
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    ——
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

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