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WR-99210
CAS No. 30711-93-4
WR-99210( 6,6-Dimethyl-1-[3-(2,4,5-trichlorophenoxy)propoxy]-1,6-dihydro-1,3,5-triazine-2,4-diamine | WR99210 hydrochloride(47326-86-3 free base) )
Catalog No. M24237 CAS No. 30711-93-4
WR-99210 is a potent inhibitor of?Plasmodium falciparum?dihydrofolate reductase (pfDHFR), which is a major malarial drug target.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 259 | In Stock |
|
| 10MG | 372 | In Stock |
|
| 25MG | 619 | In Stock |
|
| 50MG | 881 | In Stock |
|
| 100MG | 1188 | In Stock |
|
| 500MG | 2367 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameWR-99210
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NoteResearch use only, not for human use.
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Brief DescriptionWR-99210 is a potent inhibitor of?Plasmodium falciparum?dihydrofolate reductase (pfDHFR), which is a major malarial drug target.
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DescriptionWR-99210 is a potent inhibitor of?Plasmodium falciparum?dihydrofolate reductase (pfDHFR), which is a major malarial drug target. It has subnanomolar potency for the wild type, double mutant and quadruple mutant dihydrofolate reductases.
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In Vitro——
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In Vivo——
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Synonyms6,6-Dimethyl-1-[3-(2,4,5-trichlorophenoxy)propoxy]-1,6-dihydro-1,3,5-triazine-2,4-diamine | WR99210 hydrochloride(47326-86-3 free base)
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PathwayOthers
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TargetOther Targets
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RecptorpfDHFR
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Research Area——
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Indication——
Chemical Information
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CAS Number30711-93-4
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Formula Weight431.14
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Molecular FormulaC14H19Cl4N5O2
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Purity>98% (HPLC)
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Solubility——
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SMILESNC1=NC(N)=NC(C)(C)N1OCCCOC2=CC(Cl)=C(Cl)C=C2Cl.[H]Cl
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Canfield C J , Milhous W K , Ager A L , et al. PS-15: a potent, orally active antimalarial from a new class of folic acid antagonists.[J]. American Journal of Tropical Medicine & Hygiene, 1993, 49(1):121.
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