WHI-P131

CAS No. 202475-60-3

WHI-P131( Janex 1 )

Catalog No. M13153 CAS No. 202475-60-3

Janex-1 is a cell-permeable, reversible, potent, ATP-competitive, and specific inhibitor of JAK3.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 45 In Stock
5MG 76 In Stock
10MG 138 In Stock
25MG 235 In Stock
50MG 421 In Stock
100MG 617 In Stock
500MG 1305 In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    WHI-P131
  • Note
    Research use only, not for human use.
  • Brief Description
    Janex-1 is a cell-permeable, reversible, potent, ATP-competitive, and specific inhibitor of JAK3.
  • Description
    Janex-1 is a cell-permeable, reversible, potent, ATP-competitive, and specific inhibitor of JAK3 (IC50 = 78μM); has no effect on JAK1, JAK2, or Zap/Syk or SRC tyrosine kinases.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    Janex 1
  • Pathway
    Angiogenesis
  • Target
    JAK
  • Recptor
    JAK3| JAK3
  • Research Area
    Cancer
  • Indication
    ——

Chemical Information

  • CAS Number
    202475-60-3
  • Formula Weight
    297.31
  • Molecular Formula
    C16H15N3O3
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO: 10 mM
  • SMILES
    OC1=CC=C(NC2=C3C=C(OC)C(OC)=CC3=NC=N2)C=C1
  • Chemical Name
    4-[(6,7-dimethoxy-4-quinazolinyl)amino]-phenol

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Sudbeck EA, et al. Clin Y Res. 1999 Jun;5(6): 1569-82.
molnova catalog
related products
  • PRN371

    PRN371 is a novel potent, selective JAK3 inhibitor with IC50 of 0.5 nM.

  • ZM39923 hydrochlorid...

    ZM39923 is a potent, selective JAK3 inhibitor with pIC50 of 7.1.

  • WYE-151650

    WYE-151650 is a novel potent, selective JAK3 inhibitor with IC50 of 0.8 nM, displays 36-, 14-, and 34-fold selectivity against JAK-1, JAK-2, and Tyk-2, respectively.