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WAY-200070

CAS No. 440122-66-7

WAY-200070 ( WAY200070;WAY 200070 )

Catalog No. M14497 CAS No. 440122-66-7

WAY-200070 is a potent, highly selective ERβ agonist with IC50 of 3 nM, displays 68-fold selectivity over ERα (IC50=260 nM).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    WAY-200070
  • Note
    Research use only, not for human use.
  • Brief Description
    WAY-200070 is a potent, highly selective ERβ agonist with IC50 of 3 nM, displays 68-fold selectivity over ERα (IC50=260 nM).
  • Description
    WAY-200070 is a potent, highly selective ERβ agonist with IC50 of 3 nM, displays 68-fold selectivity over ERα (IC50=260 nM); induces galanin expression within gonadotropin hormone-releasing hormone-immunoreactive neurons in the female rat brain, causes and learn the socially acquired preferenc in mice, deonstrates the anxiolytic-like and antidepressant-like effects in vivo.
  • Synonyms
    WAY200070;WAY 200070
  • Pathway
    Endocrinology/Hormones
  • Target
    Estrogen Receptor/ERR
  • Recptor
    ERRα;ERRβ
  • Research Area
    Neurological Disease
  • Indication
    ——

Chemical Information

  • CAS Number
    440122-66-7
  • Formula Weight
    306.11
  • Molecular Formula
    C13H8BrNO3
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO: ≥ 31 mg/mL
  • SMILES
    O=C1C=C/C(C=C1)=C2OC3=C(Br)C=C(O)C=C3N/2
  • Chemical Name
    5-Benzoxazolol, 7-bromo-2-(4-hydroxyphenyl)-

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Hughes ZA, et al. Neuropharmacology. 2008 Jun;54(7):1136-42.
2. Clipperton AE, et al. Neuropsychopharmacology. 2008 Sep;33(10):2362-75.
3. Malamas MS, et al. J Med Chem. 2004 Oct 7;47(21):5021-40.
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