WAY-118959-A( —— )

Catalog No. M35317 CAS No. 315703-81-2

WAY-118959-A is a potential microtubule acetylation inhibitor.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

Size	Price / USD	Stock	Quantity
2MG	178	Get Quote
5MG	255	Get Quote
10MG	375	Get Quote
25MG	545	Get Quote
50MG	762	Get Quote
100MG	1017	Get Quote
200MG	1377	Get Quote
500MG	Get Quote	Get Quote
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Biological Information

Product Name

WAY-118959-A
Note

Research use only, not for human use.
Brief Description

WAY-118959-A is a potential microtubule acetylation inhibitor.
Description

GM-90257 is a microtubule acetylation inhibitor that binds directly to α-tubulin. GM-90257 prevents the recruitment of α-tubulin acetyltransferase 1 (αTAT1) to the K40 residue in α-tubulin. GM-90257 causes the apoptosis of MDA-MB-231 cells with weaker effects on MCF-10A or MCF-7 cells, which have a relatively low level of microtubule acetylation.
In Vitro

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In Vivo

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Synonyms

——
Pathway

Others
Target

Other Targets
Recptor

Microtubule Associated
Research Area

——
Indication

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Chemical Information

CAS Number

315703-81-2
Formula Weight

342.44
Molecular Formula

C16H14N4OS2
Purity

>98% (HPLC)
Solubility

——
SMILES

COC1=CC=C(NC2=NC(=CS2)C2=C(C)N=C3SC=CN23)C=C1
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Ahreum Kwon, et al. Potent Small-Molecule Inhibitors Targeting Acetylated Microtubules as Anticancer Agents Against Triple-Negative Breast Cancer. Biomedicines. 2020 Sep 9;8(9):338. ?

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