Cart
sales@molnova.com
WAY-118959-A
CAS No. 315703-81-2
WAY-118959-A( —— )
Catalog No. M35317 CAS No. 315703-81-2
WAY-118959-A is a potential microtubule acetylation inhibitor.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 178 | Get Quote |
|
| 5MG | 255 | Get Quote |
|
| 10MG | 375 | Get Quote |
|
| 25MG | 545 | Get Quote |
|
| 50MG | 762 | Get Quote |
|
| 100MG | 1017 | Get Quote |
|
| 200MG | 1377 | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
-
Product NameWAY-118959-A
-
NoteResearch use only, not for human use.
-
Brief DescriptionWAY-118959-A is a potential microtubule acetylation inhibitor.
-
DescriptionGM-90257 is a microtubule acetylation inhibitor that binds directly to α-tubulin. GM-90257 prevents the recruitment of α-tubulin acetyltransferase 1 (αTAT1) to the K40 residue in α-tubulin. GM-90257 causes the apoptosis of MDA-MB-231 cells with weaker effects on MCF-10A or MCF-7 cells, which have a relatively low level of microtubule acetylation.
-
In Vitro——
-
In Vivo——
-
Synonyms——
-
PathwayOthers
-
TargetOther Targets
-
RecptorMicrotubule Associated
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number315703-81-2
-
Formula Weight342.44
-
Molecular FormulaC16H14N4OS2
-
Purity>98% (HPLC)
-
Solubility——
-
SMILESCOC1=CC=C(NC2=NC(=CS2)C2=C(C)N=C3SC=CN23)C=C1
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Ahreum Kwon, et al. Potent Small-Molecule Inhibitors Targeting Acetylated Microtubules as Anticancer Agents Against Triple-Negative Breast Cancer. Biomedicines. 2020 Sep 9;8(9):338. ?
molnova catalog
related products
-
Catharanthine sulfat...
Catharanthine inhibits nicotinic receptor-mediated diaphragm contractions.
-
(Iso)-RJW100
(Iso)-RJW100 is a potent liver receptor homolog 1 (LRH-1, NR5A2) and steroidogenic factor-1 (SF-1, NR5A1) agonist with pEC 50 s of 6.4 and 7.2, respectively.
-
STM2120
STM2120 is a potent METTL3 inhibitor (IC50: 64.5 μM) with inhibitory effect on METTL14.
