VinSpinIn ( —— )

Catalog No. M17065 CAS No.

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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Product Name

VinSpinIn
Note

Research use only, not for human use.
Brief Description

VinSpinIn is a potent, cell active chemical probe for the Spin family protein with Kd of 10-130 nM for across the family.
Description

VinSpinIn is a potent, cell active chemical probe for the Spin family protein with Kd of 10-130 nM for across the family, displays >300-fold selectivity over a panel of methyltransferases; demonstrates dose dependant inhibition of the Spin1-H3 interaction in a NanoBRET cellular target engagement assay.
Synonyms

——
Pathway

Chromatin/Epigenetic
Target

HMTase
Recptor

HMTase
Research Area

——
Indication

——

CAS Number

--
Formula Weight

738.98
Molecular Formula

C42H58N8O4
Purity

>98% (HPLC)
Solubility

——
SMILES

O=C(N1CCC(CCN2CCCC2)CC1)CN3N=NC(CCOC4=CC5=C(CN(CCCOC6=CC7=C(C=C6OCC8CC8)C(C)(C)C(N)=N7)C5)C=C4)=C3
Chemical Name

2-(4-(2-((2-(3-((2-amino-5-(cyclopropylmethoxy)-3,3-dimethyl-3H-indol-6-yl)oxy)propyl)isoindolin-5-yl)oxy)ethyl)-1H-1,2,3-triazol-1-yl)-1-(4-(2-(pyrrolidin-1-yl)ethyl)piperidin-1-yl)ethan-1-one