Vidarabine( Adenine Arabinoside | Ara-A | 9-β-D-Arabinofuranosyl adenine | Arabinosyladenine | NSC 247519 | NSC 404241 | Vira-A )

Catalog No. M15012 CAS No. 5536-17-4

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HPLC

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Product Name

Vidarabine
Note

Research use only, not for human use.
Brief Description

Vidarabine is an antiviral drug which is active against herpes simplex and varicella zoster viruses.
Description

Vidarabine is an antiviral drug which is active against herpes simplex and varicella zoster viruses.(In Vitro):Vidarabine (Ara-A) is a nucleoside antibiotic isolated from Streptomyces antibioticus. It has some antineoplastic properties and has broad spectrum activity against DNA viruses in cell cultures and significant antiviral activity against infections caused by a variety of viruses such as the herpes viruses, the vaccinia VIRUS and varicella zoster virus.
In Vitro

Vidarabine (Ara-A) is a nucleoside antibiotic isolated from Streptomyces antibioticus. It has some antineoplastic properties and has broad spectrum activity against DNA viruses in cell cultures and significant antiviral activity against infections caused by a variety of viruses such as the herpes viruses, the vaccinia VIRUS and varicella zoster virus.
In Vivo

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Synonyms

Adenine Arabinoside | Ara-A | 9-β-D-Arabinofuranosyl adenine | Arabinosyladenine | NSC 247519 | NSC 404241 | Vira-A
Pathway

Cell Cycle/DNA Damage
Target

DNA/RNA Synthesis
Recptor

DNA polymerase| DNA polymerase| Tyrosine Kinases
Research Area

Infection
Indication

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CAS Number

5536-17-4
Formula Weight

267.24
Molecular Formula

C10H13N5O4
Purity

>98% (HPLC)
Solubility

Water: 3 mg/mL (11.22 mM); DMSO: 53 mg/mL (198.32 mM)
SMILES

O[C@@H]1[C@H](N2C=NC3=C(N)N=CN=C23)O[C@H](CO)[C@H]1O
Chemical Name

(2R,3S,4S,5R)-2-(6-amino-9H-purin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol

1. Suzuki M, et al. Antiviral Res. 2006 Nov; 72(2):157-6

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