Verubulin( —— )

Catalog No. M33530 CAS No. 827031-83-4

Verubulin (MPC 6827) is a potent microtubule blocker with cytotoxic and potentially anticancer activity that disrupts newly formed blood vessels in xenografts, and can be used to image microtubules (MTs) using positron emission tomography (PET).

Purity : >98% (HPLC)

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Biological Information

Product Name

Verubulin
Note

Research use only, not for human use.
Brief Description

Verubulin (MPC 6827) is a potent microtubule blocker with cytotoxic and potentially anticancer activity that disrupts newly formed blood vessels in xenografts, and can be used to image microtubules (MTs) using positron emission tomography (PET).
Description

Verubulin (MPC-6827) is a microtubule-disrupting agent with potent and broad-spectrum in vitro and in vivo cytotoxic activities, and acts as a promising candidate for the treatment of multiple cancer types.
In Vitro

——
In Vivo

——
Synonyms

——
Pathway

Others
Target

Other Targets
Recptor

Microtubule Associated
Research Area

——
Indication

——

Chemical Information

CAS Number

827031-83-4
Formula Weight

279.34
Molecular Formula

C17H17N3O
Purity

>98% (HPLC)
Solubility

In Vitro:?DMSO : 100 mg/mL (357.99 mM; Ultrasonic )
SMILES

N=1C(=NC(=C2C=CC=CC12)N(C3=CC=C(OC)C=C3)C)C
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Kasibhatla S, et al. MPC-6827: a small-molecule inhibitor of microtubule formation that is not a substrate for multidrug resistance pumps. Cancer Res. 2007 Jun 15;67(12):5865-71.?

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