Vercirnon

Research use only, not for human use.

Vercirnon is a selective and potent antagonist of CCR9 (IC50: 10 nM). It is also used in the research of inflammatory bowel diseases.

Vercirnon is a selective and potent antagonist of CCR9 (IC50: 10 nM). It is also used in the research of inflammatory bowel diseases.

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Animal Model:C57BL/6 mice (TNFΔARE Mouse Model of Terminal Ileitis)Dosage:10, 50 mg/kg Administration:Subcutaneous; twice per day; starting at 2 weeks of age until 12 weeks of age Result:Resulted in complete protection from the severe inflammation associated with TNF- overexpression at 50 mg/kg. A similar protective effect was also noted with a lower dose.

GSK-1605786 | CCX282-B | Traficet-EN

Others

Other Targets

CCR9

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698394-73-9

444.93

C22H21ClN2O4S

>98% (HPLC)

DMSO : 22.25 mg/mL (50 mM)

CC(C)(C)c(cc1)ccc1S(Nc(ccc(Cl)c1)c1C(c(cc1)cc[n+]1[O-])=O)(=O)=O

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(-20℃)

With Ice Pack

≥ 2 years