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Vercirnon

CAS No. 698394-73-9

Vercirnon ( GSK-1605786; CCX282-B; Traficet-EN )

Catalog No. M24714 CAS No. 698394-73-9

Vercirnon is a selective and potent antagonist of CCR9 (IC50: 10 nM). It is also used in the research of inflammatory bowel diseases.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Vercirnon
  • Note
    Research use only, not for human use.
  • Brief Description
    Vercirnon is a selective and potent antagonist of CCR9 (IC50: 10 nM). It is also used in the research of inflammatory bowel diseases.
  • Description
    Vercirnon is a selective and potent antagonist of CCR9 (IC50: 10 nM). It is also used in the research of inflammatory bowel diseases.
  • Synonyms
    GSK-1605786; CCX282-B; Traficet-EN
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    CCR9
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    698394-73-9
  • Formula Weight
    444.9
  • Molecular Formula
    C22H21ClN2O4S
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO : 22.25 mg/mL (50 mM)
  • SMILES
    CC(C)(C)c(cc1)ccc1S(Nc(ccc(Cl)c1)c1C(c(cc1)cc[n+]1[O-])=O)(=O)=O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Walters MJ, et al. Characterization of CCX282-B, an orally bioavailable antagonist of the CCR9 chemokine receptor, for treatment of inflammatory bowel disease. J Pharmacol Exp Ther. 2010 Oct;335(1):61-9.
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