
VVD-130037
CAS No. 3034880-93-5
VVD-130037( —— )
Catalog No. M37603 CAS No. 3034880-93-5
VVD-130037 is a small molecule activator specifically targeting Kelch-like ECH-associated protein 1 (KEAP1) with potential antitumor activity.
Purity : >98% (HPLC)






Size | Price / USD | Stock | Quantity |
2MG | 237 | Get Quote |
![]() ![]() |
5MG | 364 | Get Quote |
![]() ![]() |
10MG | 541 | Get Quote |
![]() ![]() |
25MG | 845 | Get Quote |
![]() ![]() |
50MG | 1150 | Get Quote |
![]() ![]() |
500MG | Get Quote | Get Quote |
![]() ![]() |
1G | Get Quote | Get Quote |
![]() ![]() |
Biological Information
-
Product NameVVD-130037
-
NoteResearch use only, not for human use.
-
Brief DescriptionVVD-130037 is a small molecule activator specifically targeting Kelch-like ECH-associated protein 1 (KEAP1) with potential antitumor activity.
-
DescriptionVVD-130037 is a small molecule activator specifically targeting Kelch-like ECH-associated protein 1 (KEAP1) with potential antitumor activity.VVD-130037 inhibits tumor growth in advanced solid tumors by degrading NRF2.
-
In Vitro——
-
In Vivo——
-
Synonyms——
-
PathwayNuclear Receptor/Transcription Factor
-
TargetKeap1-Nrf2
-
RecptorNrf2
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number3034880-93-5
-
Formula Weight344.8
-
Molecular FormulaC17H17ClN4O2
-
Purity>98% (HPLC)
-
Solubility——
-
SMILESC(C=C)(=O)N1[C@@H](COCC1)C2=CC(=CC(Cl)=C2)C=3N=C(N)C=CN3
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference



-
Nrf2-IN-1
Nrf2-IN-1 is an nuclear factor-erythroid 2-related factor 2 (Nrf2) inhibitor. Nrf2-IN-1 is developed for the research of acute myeloid leukemia (AML).Nrf2-IN-1 (Compound 4f), that inhibited Nrf2 activity.?4f had a profound growth-inhibitory effect on three AML cell lines, THP-1, HL-60 and U937, and a similar anti-growth effect in a chick embryo model.?
-
2-tert-Butyl-1,4-ben...
2-tert-Butyl-1,4-benzoquinone (TBQ), an electrophilic metabolite of butylated hydroxyanisole (BHA), causes activation of Nrf2 together with S-arylation of its negative regulator Keap1 in RAW264.7 cells.
-
RTA-408
A potent Nrf2 activator that increases expression of Nrf2 target genes and decreases expression of inflammatory mediators.