Cart
sales@molnova.com
VU591
CAS No. 1222810-74-3
VU591 ( —— )
Catalog No. M22472 CAS No. 1222810-74-3
VU591 is the first reported selective, small-molecule ROMK inhibitor(IC50 of 0.24 μM).?It inhibits potassium transport in isolated perfused rat collecting duct tubules with no effect on sodium transport.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 65 | In Stock |
|
| 10MG | 110 | In Stock |
|
| 25MG | 215 | In Stock |
|
| 50MG | 385 | In Stock |
|
| 100MG | 575 | In Stock |
|
| 500MG | 1233 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameVU591
-
NoteResearch use only, not for human use.
-
Brief DescriptionVU591 is the first reported selective, small-molecule ROMK inhibitor(IC50 of 0.24 μM).?It inhibits potassium transport in isolated perfused rat collecting duct tubules with no effect on sodium transport.
-
DescriptionVU591 is the first reported selective, small-molecule ROMK inhibitor(IC50 of 0.24 μM).?It inhibits potassium transport in isolated perfused rat collecting duct tubules with no effect on sodium transport
-
Synonyms——
-
PathwayCell Cycle/DNA Damage
-
TargetPotassium Channel
-
RecptorKir1.1;ROMK
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number1222810-74-3
-
Formula Weight368.3
-
Molecular FormulaC16H12N6O5
-
Purity>98% (HPLC)
-
SolubilityDMSO:60 mg/mL (162.91 mM; Need ultrasonic)
-
SMILES[O-][N+](=O)c1ccc2nc(COCc3nc4ccc(cc4[nH]3)[N+]([O-])=O)[nH]c2c1
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Bhave G, et al. Development of a selective small-molecule inhibitor of Kir1.1, the renal outer medullary potassium channel. Mol Pharmacol. 2011 Jan;79(1):42-50.
molnova catalog
related products
-
BMS-204352
A potent and effective calcium-sensitive opener of maxi-K potassium channels (maxi-K) with EC50 of 392 nM at -48.4 mV in HEK293 isolated outside-out membrane patches.
-
Glibornuride
Glibornuride is a blocker of ATP-sensitive K+ channel(pKi: 5.75). Glibornuride inhibits high affinity [3H]-glibenclamide binding with the potencies expected from their K+ channel activity.
-
Glimepiride
Glimepiride is the first III generation sulphonyl urea it is a very potent sulphonyl urea with long duration of action.
