VU0238429

CAS No. 1160247-92-6

VU0238429 ( SCR-1481B1 )

Catalog No. M21562 CAS No. 1160247-92-6

VU0238429 is positive allosteric modulator of muscarinic acetylcholine receptor subtype 5 (mAChR5 or M5)( EC50 : 1.16 μM).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 35 Get Quote
5MG 58 Get Quote
10MG 102 Get Quote
25MG 205 Get Quote
50MG 288 Get Quote
100MG 507 Get Quote
200MG Get Quote Get Quote
500MG Get Quote Get Quote
1G Get Quote Get Quote

Biological Information

  • Product Name
    VU0238429
  • Note
    Research use only not for human use.
  • Brief Description
    VU0238429 is positive allosteric modulator of muscarinic acetylcholine receptor subtype 5 (mAChR5 or M5)( EC50 : 1.16 μM).
  • Description
    VU0238429 is positive allosteric modulator of muscarinic acetylcholine receptor subtype 5 (mAChR5 or M5)( EC50 : 1.16 μM).
  • Synonyms
    SCR-1481B1
  • Pathway
    Endocrinology/Hormones
  • Target
    AChR
  • Recptor
    M5 mAChR
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1160247-92-6
  • Formula Weight
    351.28
  • Molecular Formula
    C17H12F3NO4
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:150 mg/mL (427.01 mM)
  • SMILES
    COc1ccc(CN2C(=O)C(=O)c3cc(OC(F)(F)F)ccc23)cc1
  • Chemical Name
    1-[(4-methoxyphenyl)methyl]-5-(trifluoromethoxy)-23-dihydro-1H-indole-23-dione

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Bridges TM et al. Discovery of the first highly M5-preferring muscarinic acetylcholine receptor ligand an M5 positive allosteric modulator derived from a series of 5-trifluoromethoxy N-benzyl isatins.
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