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Home - Products - Endocrinology/Hormones - AChR - VU0238429

VU0238429

CAS No. 1160247-92-6

VU0238429 ( SCR-1481B1 )

Catalog No. M21562 CAS No. 1160247-92-6

VU0238429 is positive allosteric modulator of muscarinic acetylcholine receptor subtype 5 (mAChR5 or M5)( EC50 : 1.16 μM).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 35 Get Quote
5MG 58 Get Quote
10MG 102 Get Quote
25MG 205 Get Quote
50MG 288 Get Quote
100MG 507 Get Quote
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Biological Information

  • Product Name
    VU0238429
  • Note
    Research use only not for human use.
  • Brief Description
    VU0238429 is positive allosteric modulator of muscarinic acetylcholine receptor subtype 5 (mAChR5 or M5)( EC50 : 1.16 μM).
  • Description
    VU0238429 is positive allosteric modulator of muscarinic acetylcholine receptor subtype 5 (mAChR5 or M5)( EC50 : 1.16 μM).
  • Synonyms
    SCR-1481B1
  • Pathway
    Endocrinology/Hormones
  • Target
    AChR
  • Recptor
    M5 mAChR
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1160247-92-6
  • Formula Weight
    351.28
  • Molecular Formula
    C17H12F3NO4
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:150 mg/mL (427.01 mM)
  • SMILES
    COc1ccc(CN2C(=O)C(=O)c3cc(OC(F)(F)F)ccc23)cc1
  • Chemical Name
    1-[(4-methoxyphenyl)methyl]-5-(trifluoromethoxy)-23-dihydro-1H-indole-23-dione

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Bridges TM et al. Discovery of the first highly M5-preferring muscarinic acetylcholine receptor ligand an M5 positive allosteric modulator derived from a series of 5-trifluoromethoxy N-benzyl isatins.
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