VU0119498 ( —— )

Catalog No. M21591 CAS No. 79183-37-2

VU0119498 is a M1 muscarinic receptor agonist (EC50 = 3.1 μM) and pan mAChR M3 M5 positive allosteric modulator (PAM)and is a neuroprotective agent.

Purity : >98% (HPLC)

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MSDS

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10MG	43	Get Quote
25MG	79	Get Quote
50MG	121	Get Quote
100MG	178	Get Quote
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Biological Information

Product Name

VU0119498
Note

Research use only not for human use.
Brief Description

VU0119498 is a M1 muscarinic receptor agonist (EC50 = 3.1 μM) and pan mAChR M3 M5 positive allosteric modulator (PAM)and is a neuroprotective agent.
Description

VU0119498 is a M1 muscarinic receptor agonist (EC50 = 3.1 μM) and pan mAChR M3 M5 positive allosteric modulator (PAM)and is a neuroprotective agent.
Synonyms

——
Pathway

Endocrinology/Hormones
Target

AChR
Recptor

mAChR
Research Area

——
Indication

——

Chemical Information

CAS Number

79183-37-2
Formula Weight

316.15
Molecular Formula

C15H10BrNO2
Purity

>98% (HPLC)
Solubility

——
SMILES

Brc1ccc(CN2C(=O)C(=O)c3ccccc23)cc1
Chemical Name

1-[(4-bromophenyl)methyl]indole-23-dione

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1.Lu Zhu Mario Rossiet al.Allosteric Modulation of β-Cell M 3 Muscarinic Acetylcholine Receptors Greatly Improves Glucose Homeostasis in Lean and Obese Mice.Proc Natl Acad Sci U S A. 2019 Sep 10;116(37):18684-18690.

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