Cart
sales@molnova.com
VT-1161
CAS No. 1340593-59-0
VT-1161( VT1161 )
Catalog No. M11365 CAS No. 1340593-59-0
VT-1161 is a potent, highly-selective, and oral fungal CYP51 inhibitor with Kd of ≤ 39 nM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 260 | In Stock |
|
| 10MG | 410 | In Stock |
|
| 25MG | 740 | In Stock |
|
| 50MG | 1233 | In Stock |
|
| 100MG | 1647 | In Stock |
|
| 200MG | 2232 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameVT-1161
-
NoteResearch use only, not for human use.
-
Brief DescriptionVT-1161 is a potent, highly-selective, and oral fungal CYP51 inhibitor with Kd of ≤ 39 nM.
-
DescriptionVT-1161 is a potent, highly-selective, and oral fungal CYP51 inhibitor with Kd of ≤ 39 nM; demonstrates >2,000-fold selectivit over human CYP51, weakly inhibits human CYP2C9, CYP2C19, and CYP3A4; exhibits excellent potency against key yeast and dermatophyte strains.Fungal Infection Phase 2 Clinical.
-
In Vitro——
-
In Vivo——
-
SynonymsVT1161
-
PathwayMicrobiology/Virology
-
TargetFungal
-
RecptorFungal
-
Research AreaInfection
-
IndicationFungal Infection
Chemical Information
-
CAS Number1340593-59-0
-
Formula Weight527.403
-
Molecular FormulaC23H16F7N5O2
-
Purity>98% (HPLC)
-
SolubilityIn Vitro:?DMSO : 250 mg/mL (474.03 mM)
-
SMILESFC(F)(COC1=CC=C(C=C1)C2=CN=C(C=C2)C(F)(F)[C@@](O)(C3=CC=C(C=C3F)F)CN4N=NN=C4)F
-
Chemical Name(R)-2-(2,4-difluorophenyl)-1,1-difluoro-3-(1H-tetrazol-1-yl)-1-(5-(4-(2,2,2-trifluoroethoxy)phenyl)pyridin-2-yl)propan-2-ol
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Hoekstra WJ, et al. Bioorg Med Chem Lett. 2014 Aug 1;24(15):3455-8.
2. Warrilow AG, et al. Antimicrob Agents Chemother. 2014 Dec;58(12):7121-7.
3. Garvey EP, et al. Antimicrob Agents Chemother. 2015 Sep;59(9):5567-73.
molnova catalog
related products
-
Penthiopyrad
A carboxamide fungicide used to control a broad spectrum of diseases on large variety of corps.
-
Corydalmine
Corydalmine (L-Corydalmine), an alkaloid isolated from roots of Corydalis Chaerophylla, inhibits spore germination of some plant pathogenic as well as saprophytic fungi.
-
Filipin complex
Filipin, produced as a mixture of related compounds known as the filipin complex (filipins I-IV) in nature.
