VPC-18005
CAS No. 2242480-48-2
VPC-18005 ( —— )
Catalog No. M28514 CAS No. 2242480-48-2
VPC-18005 is a luciferase inhibitor. VPC-18005 inhibits ERG-induced transcription and interacts directly with the ERG-ETS domain thereby disrupting the ERG binding to DNA.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
Size | Price / USD | Stock | Quantity |
5MG | 222 | Get Quote |
|
10MG | 357 | Get Quote |
|
25MG | 597 | Get Quote |
|
50MG | 851 | Get Quote |
|
100MG | 1152 | Get Quote |
|
500MG | 2313 | Get Quote |
|
1G | Get Quote | Get Quote |
|
Biological Information
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Product NameVPC-18005
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NoteResearch use only, not for human use.
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Brief DescriptionVPC-18005 is a luciferase inhibitor. VPC-18005 inhibits ERG-induced transcription and interacts directly with the ERG-ETS domain thereby disrupting the ERG binding to DNA.
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DescriptionVPC-18005 is a luciferase inhibitor. VPC-18005 inhibits ERG-induced transcription and interacts directly with the ERG-ETS domain thereby disrupting the ERG binding to DNA.(In Vitro):VPC-18005 (1 and 10 μM) produced a 20–30% decrease in the dissemination of cancer cells in zebrafsh. VPC-18005 (5 μM) inhibits pETS-luc reporter activity with IC50s of 3 and 6 μM in PNT1B-ERG and VCaP cells, respectively. VPC-18005 antagonizes the metastatic potential of ERG-expressing prostate cells and suppresses ERG reporter activity without exhibiting overt cytotoxicity. VPC-18005 inhibits migration and invasion of ERG-overexpressing cells in vitro.
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Synonyms——
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PathwayOthers
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TargetOther Targets
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Recptor——
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Research Area——
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Indication——
Chemical Information
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CAS Number2242480-48-2
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Formula Weight319.4
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Molecular FormulaC15H17N3O3S
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Purity>98% (HPLC)
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Solubility——
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SMILESN(/N=C\C1=CC=C(C(C)C)C=C1)=C\2/SC(CC(O)=O)C(=O)N2
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
molnova catalog
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