
VK3-OCH3
CAS No. 255906-59-3
VK3-OCH3( 2-[(2-Methoxy)ethylthio]-3-methyl-14-na )
Catalog No. M20174 CAS No. 255906-59-3
2-[(2-Methoxy)ethylthio]-3-methyl-14-na is a selective antitumor agent via heme oxygenase (HO-1) related mechanisms; Vitamine K3 analogue.
Purity : >98% (HPLC)






Size | Price / USD | Stock | Quantity |
2MG | 133 | In Stock |
![]() ![]() |
5MG | 191 | In Stock |
![]() ![]() |
10MG | 267 | In Stock |
![]() ![]() |
25MG | 492 | In Stock |
![]() ![]() |
50MG | 709 | In Stock |
![]() ![]() |
100MG | 972 | In Stock |
![]() ![]() |
200MG | Get Quote | In Stock |
![]() ![]() |
500MG | Get Quote | In Stock |
![]() ![]() |
1G | Get Quote | In Stock |
![]() ![]() |
Biological Information
-
Product NameVK3-OCH3
-
NoteResearch use only, not for human use.
-
Brief Description2-[(2-Methoxy)ethylthio]-3-methyl-14-na is a selective antitumor agent via heme oxygenase (HO-1) related mechanisms; Vitamine K3 analogue.
-
Description2-[(2-Methoxy)ethylthio]-3-methyl-14-na is a selective antitumor agent via heme oxygenase (HO-1) related mechanisms; Vitamine K3 analogue.
-
In VitroVK3-OCH3 (compound 5) shows cytotoxicity with IC50s of 2.43, 1.55, 10.69, 3.45, 26.24, 87.11 μM for IMR-32, LA-N-1, NB-39, SK-N-SH, HUVEC, HDF cells, respectively.VK3-OCH3 (1, 3, 10 μM) induces apoptosis and cell cycle arrest at G2/M phase in IMR-32 cells.VK3-OCH3 (0-48 h) increases the expression of HO-1 in 8~24 h, and Caveolin-1 in 48 h in IMR-32 and LA-N-1 cells.VK3-OCH3 (0-48 h) increases the expression of phospho-p38-MAPK and decreases the expression of p21 and clusterin.
-
In Vivo——
-
Synonyms2-[(2-Methoxy)ethylthio]-3-methyl-14-na
-
PathwayOthers
-
TargetOther Targets
-
RecptorOthers
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number255906-59-3
-
Formula Weight262.32
-
Molecular FormulaC14H14O3S
-
Purity>98% (HPLC)
-
SolubilityDMSO:25mg/mL(95.3 mM)
-
SMILESCOCCSC1=C(C)C(=O)c2ccccc2C1=O
-
Chemical Name2-[(2-Methoxyethyl)thio]-3-methyl-14-naphthalenedione
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
molnova catalog



related products
-
4-CMTB
4-CMTB is a selective agonist of FFA2 and GPR43.It also is a positive allosteric modulator (pEC50=6.38).
-
protoheme
protoheme used as nutrient fortifier, blood tonic and food additive for iron.
-
D(+)-Phenylalaninol
D(+)-Phenylalaninol is a useful organic compound for research related to life sciences. The catalog number is T7235 and the CAS number is 5267-64-1.